Q. Wan

Hyperglycosylation of prosaposin in tumor DCs promotes immune escape in cancer

This study shows that hyperglycosylation of prosaposin in tumor DCs leads to immune escape by impairing antigen presentation and T cell activation.

Widespread PRC barrel proteins play critical roles in archaeal cell division

This study identifies three PRC barrel proteins in Haloferax volcanii essential for archaeal cell division, showing their conservation and role in division across haloarchaea.

Direct N-Me Aziridination Reaction Enables Pinpointing C=C Bonds in Lipids with Mass Spectrometry

This paper introduces a chemical derivatization method using N-Me aziridination to precisely identify C=C bond positions in lipids via mass spectrometry.

Dual-Resolving of Lipid Positional and Geometric Isomers of C=C Bonds via Bifunctional Photocycloaddition-Photoisomerization Reaction System and Mass Spectrometry

This paper develops a bifunctional reaction system to simultaneously resolve lipid positional and geometric isomers using mass spectrometry, revealing structural patterns in bacteria and tracking changes in mouse brain ischemia.

A precise and general FRET-based method for monitoring structural transitions in protein self-organization

The paper introduces a FRET-based method to monitor structural transitions in protein self-organization, demonstrating its application to study mHttex1, DNAJB6b, and FUS assemblies.

Incidence and Characteristics of Co-infection and Secondary Infection in Patients with COVID-19

This study examines co-infection and secondary infection rates in COVID-19 patients, finding low rates of Streptococcus pneumoniae co-infections and common secondary pathogens like S. maltophilia.

KGF induces podosome formation via integrin-Erk1/2 signaling in human immortalized oral epithelial cells

This study shows KGF induces podosome formation in HIOECs through integrin-Erk1/2 signaling, enhancing epithelial adhesion and rete peg elongation.