M. Basan

Membrane potential mediates the cellular response to mechanical pressure

This study shows that membrane potential mediates cellular responses to mechanical pressure by regulating cell growth, proliferation, and elimination through Hippo and MAPK pathways.

Bacterial cell wall biosynthesis is controlled by growth rate dependent modulation of turgor pressure in E. coli

This study shows that turgor pressure in E. coli increases with growth rate and directly controls cell wall biosynthesis rate.

Plasticity of growth laws tunes resource allocation strategies in bacteria

This study shows that nutrient quality in bacteria is a plastic property shaped by proteome allocation, not a fixed biochemical constraint, and can be modified through genetic engineering.

Long-term history dependence of growth rates of E. coli after nutrient shifts

This study shows that E. coli growth rates on carbon source combinations depend on prior growth conditions, persisting for 15 generations and involving the transcription factor Mlc.

A semiconductor 96-microplate platform for real-time impedance-based high-throughput screening

This paper introduces a semiconductor microplate platform for real-time impedance-based high-throughput screening, demonstrating its ability to profile compound mechanisms of action across diverse cell types.

The energy requirements of ion homeostasis determine the lifespan of starving bacteria

This study identifies ion homeostasis as a key determinant of bacterial lifespan during starvation, showing that reducing its energetic cost extends survival.

MetA is a thermal fuse that arrests growth and protects Escherichia coli at elevated temperatures

The paper shows that E. coli uses MetA degradation to induce growth arrest and enhance survival at high temperatures.