Author

L. Peshkin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Ecology· 2 Bioengineering· 1 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:Drosophila· 4 Approach:experimental assay· 4 Approach:statistical model· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:Xenopus· 2 Assay:behavioral assay· 1

Frequent Co-Authors

L. Y. Yampolsky· 3 shared M. W. Kirschner· 3 shared A. C. Pearson· 2 shared R. A. Jonas-Closs· 2 shared A. K. Dutta· 1 shared A. Mukherjee· 1 shared A. R. Neliat· 1 shared C. Dupre· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersEcology

L. Y. Yampolsky

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Post-senescence reproductive rebound in Daphnia associated with reversal of age-related transcriptional changes

I. Y. Dua, A. C. Pearson, R. L. Lowman, L. Peshkin, L. Y. Yampolsky

The paper analyzes RNAseq data from Daphnia magna to show that post-senescence reproductive events involve reversal of age-related transcriptional changes, suggesting potential mechanisms for reproductive rejuvenation.

bioRxiv · Apr 13, 2024 · PreprintEcology

Short lifespan is one's fate, long lifespan is one's achievement: lessons from Daphnia

T. C. Beam, M. P. Bright, A. C. Pearson, I. Dua, A. K. Dutta, M. L. Smith, S. Bhadra, C. N. Strickler, S. Salman, C. E. Anderson, L. Peshkin, L. Y. Yampolsky

This study examines baseline longevity of Daphnia magna clones under various conditions, finding strong genotype-by-environment interactions and differences in lifespan extension responses to caloric restriction.

bioRxiv · Mar 30, 2024 · PreprintEcology

Membrane potential mediates the cellular response to mechanical pressure

A. Mukherjee, Y. Huang, J. Elgeti, S. Oh, J. Abreu, A. R. Neliat, J. Schuttler, D. Su, C. Dupre, N. C. Benites, X. Liu, L. Peshkin, M. Barboiu, H. Stocker, M. W. Kirschner, M. Basan

This study shows that membrane potential mediates cellular responses to mechanical pressure by regulating cell growth, proliferation, and elimination through Hippo and MAPK pathways.

bioRxiv · Nov 2, 2023Cell Biology

Effective Rapid Blood Perfusion in Xenopus

R. A. Jonas-Closs, L. Peshkin

This paper introduces a rapid blood perfusion protocol for Xenopus to improve proteomics and transcriptomics sample preparation by reducing blood contamination.

bioRxiv · Feb 1, 2023Physiology

Four novel, immortal cell lines derived from embryos of Xenopus tropicalis

G. J. Gorbsky, J. R. Daum, H. Sapkota, K. Summala, H. Yoshida, C. Georgescu, J. D. Wren, L. Peshkin, M. E. Horb

The paper describes the development of four immortal cell lines from Xenopus tropicalis embryos and characterizes their karyotype and transcriptome.

bioRxiv · Mar 1, 2022Cell Biology

"Smart Tanks": An Intelligent High-Throughput Intervention Testing Platform in Daphnia

Y. Cho, R. A. Jonas-Closs, L. Y. Yampolsky, M. W. Kirschner, L. Peshkin

The paper introduces a platform for high-throughput intervention testing in Daphnia magna, using machine learning to estimate phenotypic age under pharmacological perturbations.

bioRxiv · May 30, 2021Bioengineering

YAP independently regulates cell size and population growth dynamics via non-cell autonomous mediators

D. Mugahid, M. Kalocsay, S. Gruver, L. Peshkin, M. W. Kirschner

This study shows YAP regulates cell size and population growth through separate non-cell autonomous mechanisms, with CYR61 mediating growth but not size.

bioRxiv · Nov 29, 2018Cell Biology

Mitochondrial pseudogenes suggest repeated inter-species hybridization in hominid evolution.

K. Popadin, K. Gunbin, L. Peshkin, S. Annis, Z. Fleischmann, G. Kraytsberg, N. Markuzon, R. R. Ackermann, K. Khrapko

The paper identifies mitochondrial pseudogenes in hominids, suggesting repeated inter-species hybridization during human evolution.

bioRxiv · Oct 19, 2017Evolutionary Biology