Cancer BiologybioRxiv
Cell competition between wild-type and JAK2V617F mutant cells prevents disease relapse after stem cell transplantation in a murine model of myeloproliferative neoplasm
DOI 10.1186/s40164-021-00241-2
Author
M. Castiglione
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Biology Disciplines
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2020-2021 · peak 2/yrCo-Author Collaboration Network
7 top collaborators · 13 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
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- Cancer BiologybioRxiv
JAK2V617F mutant megakaryocytes contribute to hematopoietic aging in a murine model of myeloproliferative neoplasm
S. Lee, H. Wong, M. Castiglione…·H. Zhan
This study shows that JAK2V617F mutant megakaryocytes accelerate hematopoietic aging by affecting HSC interactions and vascular niche function in a murine MPN model.
DOI 10.1093/stmcls/sxac005 - Cancer BiologybioRxiv
Cell competition between wild-type and JAK2V617F mutant cells in a murine model of a myeloproliferative neoplasm
M. Castiglione, H. Zhang, H. Zhan
This study shows that wild-type cells alter JAK2V617F mutant cell behavior, and a mutant microenvironment enables mutant clonal expansion in MPN.
DOI 10.1016/j.exphem.2021.06.003