Author

H. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Adoum· 1 shared A. T. Soderholm· 1 shared A. To· 1 shared B. Moron· 1 shared B. N. Keller· 1 shared B. S. Beresford-Jones· 1 shared C. A. Hoeffer· 1 shared C. Brandt· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Adoum

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids

C. W. Chau, A. To, R. K. H. Au-Yeung, K. Tang, Y. Xiang, D. Ruan, L. Zhang, H. Wong, S. Zhang, M. T. Au, S. Chung, E. Song, D.-H. Choi, P. Liu, S. Yuan, , R. Sugimura

This study shows SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids, upregulating interferon signaling linked to cytokine release syndrome.

Scientific Reports · Apr 16, 2024Peer-reviewedImmunology

Proteins containing 6-crossing knot types andtheir folding pathways

M. Sikora, E. Flapan, H. Wong, P. Rubach, W. Garstka, S. Niewieczerzal, E. J. Rawdon, J. I. Sulkowska

This paper analyzes 6-crossing protein knots using AlphaFold 2 predictions and a coarse-grained model, identifying two distinct folding mechanisms for the 63 knot.

bioRxiv · Jun 16, 2023 · PreprintBiophysics

JAK2V617F mutant megakaryocytes contribute to hematopoietic aging in a murine model of myeloproliferative neoplasm

S. Lee, H. Wong, M. Castiglione, M. Murphy, K. Kaushansky, H. Zhan

This study shows that JAK2V617F mutant megakaryocytes accelerate hematopoietic aging by affecting HSC interactions and vascular niche function in a murine MPN model.

bioRxiv · Aug 24, 2021Cancer Biology

Chasing the origin of SARS-CoV-2 in Canada's COVID-19 cases: A genomics study

C. P. Sjaarda, N. Rustom, D. Huang, S. Perez-Patrigeon, M. L. Hudson, H. Wong, T. H. Guan, M. Ayub, C. N. Soares, R. I. Colautti, G. A. Evans, P. M. Sheth

This study analyzes SARS-CoV-2 genomes from early Canadian cases to trace viral origins and transmission patterns using phylogenetic analysis.

Scientific Reports · Feb 12, 2021Peer-reviewedMicrobiology

Novel gut pathobionts confound results in a widely used mouse model of human inflammatory disease

S. C. Forster, S. Clare, B. S. Beresford-Jones, K. Harcourt, G. Notley, M. Stares, N. Kumar, A. T. Soderholm, A. Adoum, H. Wong, B. Moron, C. Brandt, G. Dougan, D. J. Adams, K. J. Maloy, , T. D. Lawley

The paper identifies two novel gut bacteria that influence disease variability in a mouse model of inflammatory bowel disease.

bioRxiv · Feb 9, 2021 · PreprintMicrobiology

AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity

J. Levenga, H. Wong, R. A. Milstead, B. N. Keller, L. E. LaPlante, C. A. Hoeffer

bioRxiv · Jul 25, 2017Cell Biology