Author

M. D. Cordero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Sanz· 3 shared B. Castejon-Vega· 3 shared E. Alcocer-Gomez· 3 shared G. Mbalaviele· 3 shared A. Gallardo-Orihuela· 2 shared B. Ryffel· 2 shared C. Wang· 2 shared I. Muela-Zarzuela· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

A. Sanz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype

I. Muela-Zarzuela, J. M. Suarez-Rivero, A. Gallardo-Orihuela, C. Wang, K. Izawa, M. de Gregorio-Procopio, I. Couillin, B. Ryffel, J. Kitaura, A. Sanz, T. von Zglinicki, G. Mbalaviele, M. D. Cordero

This study shows that NLRP1 inflammasome promotes senescence and SASP through GSDMD-dependent regulation of p16, p21, p53, and SASP expression.

bioRxiv · Feb 6, 2023 · PreprintImmunology

NEK7 activates the NLRP1 Inflammasome

I. Muela-Zarzuela, A. Gallardo-Orihuela, A. Pino-Angeles, J. M. Suarez-Rivero, D. Boy-Ruiz, M. de Gregorio-Procopio, J. Oroz, G. Mbalaviele, M. D. Cordero

This study shows NEK7 activates NLRP1 inflammasome independently of NLRP3, affecting IL-1β maturation in Nek7-deficient cells.

bioRxiv · Dec 21, 2022 · PreprintImmunology

L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation

B. Castejon-Vega, A. Rubio, A. J. Perez-Pulido, J. L. Quiles, J. D. Lane, B. Fernandez Dominguez, M. B. Cachon-Gonzalez, C. Martin.Ruiz, A. Sanz, T. M. Cox, E. Alcocer-Gomez, M. D. Cordero

This study shows L-arginine improves autophagy defects in GM2 gangliosidoses by restoring mTOR signaling and reducing lysosomal permeability in patient fibroblasts.

bioRxiv · May 28, 2021Cell Biology

NLRP3 inflammasome inhibition rescues Hutchinson-Gilford Progeria cellular phenotype and extend longevity of an animal model

E. Alcocer-Gomez, B. Castejon-Vega, J. Nunez-Vasco, D. Lendines-Cordero, J. M. Navarro-Pando, M. D. Cordero

This study shows that inhibiting the NLRP3 inflammasome improves cellular phenotype and extends lifespan in HGPS animal models.

bioRxiv · Sep 9, 2020 · PreprintImmunology

Inhibition of the NLRP3 inflammasome prevents ovarian aging

J. M. Navarro-Pando, E. Alcocer-Gomez, B. Castejon-Vega, J. Muntane, C. Wang, H. M. Hoffman, A. Sanz, G. Mbalaviele, B. Ryffel, M. D. Cordero

This study shows that inhibiting the NLRP3 inflammasome improves ovarian function and fertility in aging mice by enhancing AMH, autophagy, and reducing FSH and estradiol levels.

bioRxiv · Apr 26, 2020Immunology