Author

D. Weitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:biophysical modeling· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:genome assembly· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Chen· 2 shared T. Knowles· 2 shared A. Basu· 1 shared A. Elosegui-Artola· 1 shared A. Feldman· 1 shared A. Fischer· 1 shared A. Garaizar Suarez· 1 shared A. Gupta· 1 shared

Activity by Year

2016-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBioengineering

A. Chen

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Phase separated liquid vimentin droplets stabilize actin fibers through wetting

A. Basu, T. Krug, B. F. du Pont, Q. Huang, S. Sun, S. A. Adam, R. D. Goldman, D. Weitz

This study shows vimentin forms liquid droplets that stabilize actin fibers by wetting them, and this behavior is observed in both a mutant and wild-type vimentin.

bioRxiv · Jun 15, 2024Biophysics

High-sensitivity whole-genome recovery of single viral species in environmental samples

L. Chen, A. Chen, X. D. Zhang, M. T. Saenz, H.-S. Han, Y. Xiao, G. Xiao, J. M. Pipas, D. Weitz

This paper develops a method to recover complete viral genomes from environmental samples with high sensitivity, achieving 100% recovery of a spiked-in virus and 99.4% for a larger virus.

bioRxiv · Nov 13, 2023 · PreprintBioengineering

Adsorption of RNA to interfaces of biomolecular condensates enables wetting transitions

N. A. Erkamp, M. Farag, D. Qian, T. Sneideris, T. J. Welsh, H. Ausserwoger, D. Weitz, R. V. Pappu, T. Knowles

This study shows that pyrimidine-rich RNAs act as adsorbents enabling wetting transitions in condensates formed by purine-rich RNAs, revealing orientation differences between scaffolds and adsorbents.

bioRxiv · Jan 12, 2023 · PreprintBiophysics

Solid/liquid coexistence during aging of FUS condensates

Y. Shen, A. Chen, W. Wang, Y. Shen, F. S. Ruggeri, S. Aime, Z. Wang, S. S. Qamar, J. R. Espinosa, A. Garaizar Suarez, P. St George-Hyslop, R. Collepardo-Guevara, D. Weitz, D. Vigolo, T. Knowles

The paper shows that FUS condensates during aging exhibit solid/liquid coexistence, with the transition initiated at the interface between dense and dilute phases.

bioRxiv · Aug 15, 2022Biophysics

Recovery of structural integrity of epithelial monolayer in response to massive apoptosis-induced defects

Y. Yuan, Y. L. Han, J. Xia, H. Li, C. Tang, F. Ye, D. Weitz, M. Guo

This study shows that epithelial monolayers recover structural integrity after apoptosis-induced defects through enhanced cell spreading, migration, and traction forces.

bioRxiv · Aug 8, 2022 · PreprintBiophysics

Matrix viscoelasticity controls spatio-temporal tissue organization

A. Elosegui-Artola, A. Gupta, A. J. Najibi, B. R. Seo, R. Garry, C. M. Tringides, I. de Lazaro, M. Darnell, W. Gu, Q. Zhou, D. Weitz, L. Mahadevan, D. Mooney

This study shows how matrix viscoelasticity influences tissue organization by causing symmetry breaking and branching in epithelial cell aggregates.

bioRxiv · Jan 19, 2022 · PreprintBiophysics

Tuning the course of evolution on the biophysical fitness landscape of an RNA virus

A. Rotem, A. Serohijos, C. Chang, J. Wolfe, A. Fischer, T. Mehoke, H. Zhang, Y. Tao, L. Ung, J.-M. Choi, A. Kolawole, S. Koehler, S. Wu, P. Thielen, N. Cui, , E. Shakhnovich

This study predicts the evolutionary pathway of norovirus escaping antibodies using a biophysical fitness model, validated by experimental evolution in bulk culture and microfluidics.

bioRxiv · Dec 8, 2016Evolutionary Biology