M. Davila

Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells

The paper shows that mitochondrial DNA replication stalling increases G-quadruplex formation, which blocks replication forks and leads to mtDNA loss in human cells.

CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations

The paper analyzes CITEseq data from NSCLC lesions to identify an immune cell activation module linked to tumor antigen load and TP53 mutations.

A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer

The paper describes a modified Helios mass cytometer protocol that improves data quality and reduces inter-instrument variability in multi-center studies.