Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC
S. Liu, L. Li, F. Zhang, B. van Sambeek, E. Appleton, A. H. M. Ng, P. Khoshakhlagh, Y. Chen, M. Garcia-Corral, C.-T. Wu, J. Y. Huang, Y. Tan, G. Chao, J. Aach, J. Tam, , G. Church
This study uses iterative transcription factor screening to generate microglia-like cells from human iPSCs, identifying a combination of TFs that efficiently differentiate iPSCs into microglia-like cells within 4 days.
bioRxiv · Jun 3, 2022Bioengineering