M. Gut

The hepatocyte Epidermal Growth Factor Receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche

This study shows that inhibiting EGFR in hepatocytes reduces liver fibrosis by altering immune cell populations and molecular mechanisms involved in inflammation and fibrogenesis.

Whole genomes of the amazonian Cacajao reveal complex connectivity and fast differentiation driven by high environmental dynamism

The paper presents whole genome data from 48 uakari monkeys, revealing genetic differentiation between bald and black uakaris due to environmental factors.

The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution

The paper presents the chromosome-level genome assembly of a newly described Nematomorpha species, providing genomic resources for studying Ecdysozoa evolution and parasitic lifestyles.

Designed Ankyrin Repeat Proteins for detecting prostate-specific antigen expression in vivo

This paper develops PSA-specific DARPins for in vivo imaging to monitor drug resistance in prostate cancer.

A TetR-like transcriptional regulator in Stenotrophomonas maltophilia involved in fatty acid metabolism is controlled by quorum sensing signals

This study identifies a TetR-like regulator in S. maltophilia that links quorum sensing signals to fatty acid metabolism and bacterial fitness during growth phase transitions.

Genomic adaptations to aquatic and aerial life in mayflies and the origin of wings in insects

This study analyzes the genome and gene expression of mayflies to uncover genomic adaptations related to aquatic and aerial life and the origin of wings in insects.

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

The paper shows PMDs are hypervariable in breast cancer and drive CGI hypermethylation, but do not significantly repress cancer genes.