Author

A. Chaudhuri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Immunology· 2 Biochemistry· 1 Ecology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

K. Bhojak· 2 shared K. Lee· 2 shared P. Chakraborty· 2 shared V. Kode· 2 shared A. Lin· 1 shared A. Nair· 1 shared A. Ramesh· 1 shared A. Sagar· 1 shared

Activity by Year

2017-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

K. Bhojak

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Author profile →

9 papers

Recent·Most cited

Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate

P. Borar, T. Biswas, A. Chaudhuri, P. T. Rao, S. Raychaudhuri, T. Huxford, S. Chakrabarti, G. Ghosh, S. Polley

This study identifies dual-specific autophosphorylation in IKK2, showing tyrosine autophosphorylation and ATP-contacting residue K44 regulate substrate specificity for IκBα phosphorylation during NF-κB activation.

eLife · Jun 30, 2025Peer-reviewedBiochemistry

β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain

S. S. Madhavan, S. Roa Diaz, S. Peralta, M. Nomura, C. D. King, A. Lin, D. Bhaumik, S. Shah, T. Blade, W. Gray, M. Chamoli, B. Eap, O. Panda, D. Diaz, T. Y. Garcia, , J. C. Newman

This study identifies β-hydroxybutyrate as a metabolic regulator of protein solubility in aging and Alzheimer's disease, showing it reduces insolubility of pathological proteins like amyloid-β.

bioRxiv · Jul 3, 2023Physiology

Decoding optimal ligand design for multicomponent condensates

S. K. K. Galagedera, T. P. Dao, S. E. Enos, A. Chaudhuri, J. D. Schmit, C. A. Castaneda

This study identifies optimal polyubiquitin ligand architectures that promote UBQLN2 phase separation by analyzing the energetic penalties and spatial configurations of Ub units.

bioRxiv · Mar 13, 2023Biophysics

The role of myosin contractility as a molecular determinant of traction force regulation

D. Ghosh, S. Ghosh, A. Chaudhuri

This study presents an analytical model of myosin contractility's role in traction force regulation, showing how varying molecular parameters leads to different stability states and matches experimental observations.

bioRxiv · Aug 30, 2022 · PreprintBiophysics

Tip-links serve as force-pass filter to fulfil the role of gating-springs

N. Arora, J. P. Hazra, S. Roy, G. K. Bhati, S. Gupta, A. Chaudhuri, A. Sagar, S. RAKSHIT

The paper investigates the mechanical behavior of tip-links in hearing, showing they act as low-force pass filters through slip-ideal-slip bond dynamics and their role in gating-springs.

bioRxiv · Aug 10, 2022 · PreprintBiophysics

Immunodominant influenza epitope GILGFVFTL engage common and divergent TCRs when presented as a 9-mer or a 15-mer peptide

A. Chaudhuri, K. Bhojak, V. Kode, C. M. Miriam, K. Lee, P. Chakraborty

The paper compares T-cell engagement with a 9-mer and 15-mer version of the GILGFVFTL epitope to assess differences in TCR diversity and activation kinetics.

bioRxiv · Jul 11, 2022 · PreprintImmunology

Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

S. Mahajan, K. Bhojak, V. Kode, C. M. Magdalene, M. Manoharan, K. Lee, A. Ramesh, S. H. V, A. Srivastava, R. Sathian, P. Kumar, T. Khan, P. Chakraborty, A. Chaudhuri

This study identifies immunodominant T-cell epitopes in SARS-CoV-2 spike antigen and shows pre-existing T-cell immunity in unexposed individuals, suggesting prior exposure to common viruses like Influenza and CMV.

bioRxiv · Nov 3, 2020Immunology

Dynein catch bond as a mediator of codependent bidirectional cellular transport

P. Puri, N. Gupta, S. Chandel, S. Naskar, A. Nair, A. Chaudhuri, M. K. Mitra, S. Muhuri

The paper resolves the paradox of codependent bidirectional transport by showing dynein's catchbonding behavior enables regulatory mechanisms in motor function.

bioRxiv · May 10, 2018Biophysics

Computational Complex Predator-Prey Dynamics

A. Chaudhuri, S. S. Hassan

The paper investigates complex predator-prey dynamics with mature-immature stage structure and compares them to existing models.

bioRxiv · Jun 18, 2017Ecology