T. Khan

IL-3-driven T cell-basophil crosstalk enhances anti-tumor immunity

This study shows that IL-3 enhances anti-tumor immunity by promoting CTL-basophil interactions, improving CTL activity and tumor suppression.

Solvent based fractional biosynthesis, phytochemical analysis and biological activity of silver nanoparticles obtained from extract of Salvia moorcroftiana

This study synthesizes silver nanoparticles from Salvia moorcroftiana extracts using different solvents and evaluates their antibacterial activity against multidrug-resistant bacteria.

Cell behaviors underlying Myxococcus xanthus aggregate coarsening

This paper identifies cell behaviors driving aggregate dispersal in Myxococcus xanthus using microscopy and modeling, showing reversal bias changes correlate with aggregate size and genetic control.

Glycogen phosphorylase inhibition alongside taxol chemotherapy synergistically elicits ferroptotic cell death in clear cell ovarian and kidney cancers

The paper shows that inhibiting glycogen phosphorylase with CP91149 synergizes with taxol to induce ferroptotic cell death in clear cell ovarian and kidney cancers.

A novel method for sampling subgingival microbiome - a comparative metatranscriptomic study

The paper develops a novel subgingival microbiome sampling method using supragingival swabs and validates it through metatranscriptomic analysis showing comparable microbial profiles to direct subgingival samples.

Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

This study identifies immunodominant T-cell epitopes in SARS-CoV-2 spike antigen and shows pre-existing T-cell immunity in unexposed individuals, suggesting prior exposure to common viruses like Influenza and CMV.

Virome-wide serological profiling reveals association of herpesviruses with obesity

This study uses ViScan to find HSV-1 and Rhinovirus A associations with obesity in Qatari adults, but not children.

Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria

This study identifies T-bet deficiency as a cause of mycobacterial disease by impairing IFN-γ production in innate and innate-like adaptive lymphocytes.

An in vitro assessment of anti-SARS-CoV-2 activity of oral preparations of iodine complexes (RENESSANS)

This study assesses the in vitro anti-SARS-CoV-2 activity of iodine complex oral formulations, finding that higher concentrations show significant inhibition of viral replication and cytopathic effects.

Distinct antibody repertoires against endemic human coronaviruses in children and adults

The paper analyzes antibody repertoires against endemic human coronaviruses in children and adults, finding distinct epitope targets and cross-reactivity patterns.

Quantifying nucleation in vivo reveals the physical basis of prion-like phase behavior

The paper quantifies nucleation in living cells using DAmFRET and shows that kinetic barriers influence prion-like phase behavior and protein aggregation.