S. Mahajan

This study shows that LPS rapidly primes trafficking machinery in dendritic cells to enhance polarized IL-6 secretion through phosphorylation of VAMP3.

This study shows that cofilin-1 phosphorylation drives nuclear deformation and enhances dendritic cell migration through extracellular matrix.

The paper identifies GIF/metallothionein-3 as a sulfane sulfur-binding protein that regulates zinc ion binding and release through a unique C-S-S-Zn structure.

This study investigates the inactivation of SARS-CoV-2 using UVC laser radiation and identifies mechanisms involving RNA damage and disruption of spike protein function.

This study identifies seven small molecules that inhibit Chikungunya virus replication by targeting the G3BP1 protein's FGDF binding pocket.

The paper identifies herbacetin and caffeic acid phenethyl ester as inhibitors of dengue and chikungunya virus MTases, revealing their mechanism of action and antiviral efficacy.

This paper combines multi-excitation Raman spectroscopy with whole-genome sequencing to rapidly detect bacterial infections and resistance in WHO priority pathogens, achieving high accuracy in classification.

The paper reports the whole-genome sequence of an African swine fever virus isolate from India and compares it to other ASFV genomes to study genetic diversity and evolution.

The paper reports SARS-CoV-2 infection in a free-ranging Indian leopard, confirming Delta variant infection and highlighting the need for wildlife screening.

This paper introduces an in-silico widefield fluorescence microscopy technique that generates synthetic images from molecular simulations to enable cross-validation with experimental data.

The paper analyzes GC content evolution in bacteria using phylogenetic models, finding both gradual changes and evolutionary jumps in GC content across multiple bacterial groups.

TCRMatch predicts T-cell receptor specificity by comparing sequence similarity to known epitope-specific receptors in the IEDB.

This study identifies immunodominant T-cell epitopes in SARS-CoV-2 spike antigen and shows pre-existing T-cell immunity in unexposed individuals, suggesting prior exposure to common viruses like Influenza and CMV.

This paper demonstrates a label-free SHG-LSM technique for 3D imaging of collagen and other harmonophores, combining SHG with light sheet microscopy for multimodal imaging.

This paper introduces a super-resolution SHG technique that achieves nanoscale imaging of collagen architecture without fluorescent labels, revealing previously unobservable structural changes.

The paper shows that the neo-Y chromosome of Drosophila miranda has gained over 3200 genes since its formation through tandem amplification, driven by sexual and meiotic conflict.