Author

M. Murali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

J. A. MacDonald· 2 shared B. Bernard· 1 shared B. Carter· 1 shared C. Chen· 1 shared C. R. Safinya· 1 shared C. Sievers· 1 shared C. T. Allen· 1 shared C. Van Waes· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

J. A. MacDonald

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Author profile →

4 papers

Recent·Most cited

Lipids with negative spontaneous curvature decrease the solubility of the cancer drug paclitaxel in liposomes

V. M. Steffes, S. MacDonald, J. Crowe, M. Murali, K. K. Ewert, Y. Li, C. R. Safinya

This study shows that lipids with negative spontaneous curvature, like DOPE and GMO, reduce paclitaxel solubility in liposomes, making them unsuitable for drug delivery.

bioRxiv · Oct 18, 2023Biophysics

Sex dimorphism in the aged metabolic phenotype of smoothelin-like 1 (SMTNL1) deficient mice

M. Murali, N. Alabi, P. K. Chelikani, J. A. MacDonald

This study examines the sex-specific effects of SMTNL1 deletion on metabolic phenotype in aged mice, finding increased adiposity and altered energy metabolism in females.

bioRxiv · Sep 19, 2023 · PreprintBiochemistry

Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.

N. Nigam, B. Bernard, S. Kim, K. Burkitt, D. Tsai, Y. Robbins, C. Sievers, C. T. Allen, R. L. Bennett, T. T. Tettey, B. Carter, R. Bao, L. Rinaldi, M. W. Lingen, H. Sater, , V. Saloura

This study identifies SMYD3 as an epigenetic regulator that suppresses the intrinsic interferon response in HPV-negative HNSCC, offering a potential strategy to enhance immunotherapy response.

bioRxiv · Nov 4, 2022 · PreprintCancer Biology

Enhanced diastolic dysfunction but preserved systolic function after acute pressure overload in the absence of smoothelin-like 1 protein

M. Murali, S. R. Turner, D. Belke, W. C. Cole, J. A. MacDonald

This study shows that SMTNL1 knockout mice exhibit enhanced diastolic dysfunction but preserved systolic function after acute pressure overload, resembling HFpEF pathophysiology.

bioRxiv · Oct 28, 2020 · PreprintPhysiology