Author

R. L. Bennett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Riva· 3 shared D. Dupere-Richer· 3 shared J. D. Licht· 3 shared J. Li· 3 shared A. Chen· 1 shared A. Sobh· 1 shared B. Bernard· 1 shared B. Carter· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

A. Riva

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4 papers

Recent·Most cited

KDM6A Regulates Immune Response Genes in Multiple Myeloma

D. Dupere-Richer, A. Riva, S. Maji, B. G. Barwick, H. Casella, A. Sobh, G. Quickstad, J. Li, u. de, C. Piper, M. Kulis, T. Ezponda, I. Martin-Subero, G. Tonon, W. Zhang, , J. D. Licht

This study shows KDM6A regulates immune response genes in multiple myeloma by activating NLRC5 and CIITA, and its loss reduces MHC expression, which can be reversed by HDAC3 inhibitors.

bioRxiv · Feb 12, 2024Cancer Biology

Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.

N. Nigam, B. Bernard, S. Kim, K. Burkitt, D. Tsai, Y. Robbins, C. Sievers, C. T. Allen, R. L. Bennett, T. T. Tettey, B. Carter, R. Bao, L. Rinaldi, M. W. Lingen, H. Sater, , V. Saloura

This study identifies SMYD3 as an epigenetic regulator that suppresses the intrinsic interferon response in HPV-negative HNSCC, offering a potential strategy to enhance immunotherapy response.

bioRxiv · Nov 4, 2022 · PreprintCancer Biology

HDAC8-mediated inhibition of EP300 drives a neural crest-like transcriptional state that increases melanoma brain metastasis

M. F. Emmons, R. L. Bennett, A. Riva, C. Zhang, R. Macaulay, D. Dupere-Richer, B. Fang, E. Seto, J. Koomen, J. Li, A. Chen, P. Forsyth, J. Licht, K. S. M. Smalley

bioRxiv · Oct 12, 2022 · PreprintCancer Biology

DNMT3A harboring leukemia-associated mutations directs sensitivity to DNA damage at replication forks

K. Venugopal, P. Nowialis, Y. Feng, D. E. Shabashvili, C. M. Berntsen, K. I. Krajcik, C. Taragjini, Z. Zaroogian, H. L. Casellas-Roman, L. M. Posada, C. Gunaratne, J. Li, D. Dupere-Richer, R. L. Bennett, S. Pondugula, , O. A. Guryanova

This study shows that DNMT3A mutations impair replication fork recovery, leading to DNA damage and sensitivity to nucleoside analogs like cytarabine.

bioRxiv · May 28, 2021Cancer Biology