Author

M. Paschini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. L. Moye· 2 shared C. F. Kim· 2 shared V. Ya· 2 shared A. B. Vazquez· 1 shared A. F. M. Dost· 1 shared A. Shehaj· 1 shared B. Kim· 1 shared C. Aluya· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

A. L. Moye

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Airway injury induces alveolar epithelial responses mediated by macrophages

I. G. Wong, M. Paschini, J. Stark, A. B. Vazquez, V. Ya, A. L. Moye, S. M. Dang, M. F. Trovero, E. L. Thompson, S. Ahmed, F. N. Chaudhry, A. Shehaj, M. J. Rouhani, R. Bronson, S. M. Janes, , C. F. Kim

This study shows that airway injury triggers alveolar type 2 cell proliferation mediated by macrophages, revealing a myeloid-driven response in the lung.

bioRxiv · Apr 2, 2024Cell Biology

Early-stage lung adenocarcinoma is driven by an injury-associated, plastic cell state dependent on a KRAS-ITGA3-SRC axis

A. L. Moye, A. F. M. Dost, R. Ietswaart, S. Sengupta, V. Ya, C. Aluya, C. G. Fahey, S. M. Louie, M. Paschini, C. F. Kim

This study identifies an injury-associated, plastic cell state in early-stage lung adenocarcinoma driven by the KRAS-ITGA3-SRC axis, showing its role in tumor initiation and progression.

bioRxiv · Feb 27, 2024Cancer Biology

PCLAF-DREAM Drives Alveolar Cell Plasticity for Lung Regeneration

B. Kim, Y. Huang, K.-P. Ko, S. Zhang, G. Zou, J. Zhang, M. Kim, D. Little, L. V. Ellis, M. Paschini, S. Jun, K.-S. Park, J. Chen, C. Kim, J.-I. Park

This study identifies PCLAF-DREAM's role in alveolar cell plasticity during lung regeneration and shows a drug candidate can pharmacologically target this process to prevent fibrosis.

bioRxiv · Oct 11, 2022Cell Biology