Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
M. Philippi, J. Dohle, I. Watrinet, M. Holtmannspoetter, J. Li, O. Birkholz, Y. Miao, U. Rothbauer, K. C. Garcia, R. Kurre, J. Piehler, C. You
This study uses single-molecule tracking to show that Lrp6 and Ror2 co-assemble into hybrid Wnt signalosomes dynamically.
bioRxiv · Jun 18, 2024Biophysics
J. D. Stover, M. A. R. Trone, J. Weston, C. Lewis, H. Levis, M. Philippi, M. Zeidan, B. Lawrence, R. D. Bowles
This study uses CRISPR to modulate TNFR1 in rats, reducing disc degeneration and showing that TNF-alpha injection becomes therapeutic after receptor modulation.
bioRxiv · May 31, 2023Bioengineering
M. Philippi, C. P. Richter, M. Kappen, I. Watrinet, Y. Miao, M. Runge, L. Jorde, S. Korneev, M. Holtmannspoetter, R. Kurre, J. Holthuis, K. C. Garcia, A. Plueckthun, M. Steinhart, J. Piehler, C. You
The paper develops biofunctional nanodot arrays to study Wnt signalodroplets in live cells, revealing synergistic co-condensation through liquid-liquid phase separation.
bioRxiv · Jun 11, 2022Biophysics
T. Sokoya, J. Parolek, M. M. Foged, D. I. Danylchuk, M. Bozan, B. Sarkar, A. Hilderink, M. Philippi, L. D. Botto, P. A. Terhal, O. Maekitie, J. Piehler, Y. Kim, C. G. Burd, A. S. Klymchenko, , J. C. M. Holthuis
The paper shows pathogenic SMS2 variants disrupt lipid landscapes in the secretory pathway by trapping sphingomyelin in the ER and altering cholesterol and glycerophospholipid distributions.
bioRxiv · Apr 2, 2022Cell Biology
J. S. Berg, P. Pjevac, T. Sommer, C. R. T. Buckner, M. Philippi, P. Hach, M. Liebeke, M. Holtappels, F. Danza, M. Tonolla, A. Sengupta, C. Schubert, J. Milucka, M. M. M. Kuypers
This study shows that Chromatium okenii drives dark aerobic sulfide oxidation in anoxic Lake Cadagno waters, challenging the assumption that aerobic respiration is rare in such environments.
bioRxiv · Dec 22, 2018Microbiology