Author

M. Sweeney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

D. Gilham· 2 shared E. Kulikowski· 2 shared L. Fu· 2 shared A. Brombacher· 1 shared A. Goswami· 1 shared A. L. Smith· 1 shared A. Muralidharan· 1 shared A. Searle-Barnes· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. Gilham

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Author profile →

4 papers

Recent·Most cited

How many specimens make a sufficient training set for automated 3D feature extraction?

J. M. Mulqueeney, A. Searle-Barnes, A. Brombacher, M. Sweeney, A. Goswami, T. Ezard

This study determines the minimum number of training images needed for accurate 3D feature extraction using deep learning and evaluates the effectiveness of data augmentation.

bioRxiv · Jan 10, 2024 · PreprintEvolutionary Biology

Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-CoV-2 Infection in vitro

D. Gilham, A. L. Smith, L. Fu, D. Y. Moore, A. Muralidharan, S. P. M. Reid, S. C. Stotz, J. O. Johansson, M. Sweeney, N. C. Wong, E. Kulikowski, D. El-Gamal

This study shows apabetalone reduces ACE2 and DPP4 expression and inhibits SARS-CoV-2 infection in vitro, suggesting it could be a potential therapeutic for COVID-19.

bioRxiv · Mar 10, 2021Pharmacology & Toxicology

Bromodomain and Extraterminal Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection (Pre-Clinical)

R. J. Mills, S. J. Humphrey, P. R. Fortuna, M. Lor, S. R. Foster, G. A. Quaife-Ryan, R. L. Johnston, T. Dumenil, C. Bishop, R. Ruraraju, D. J. Rawle, T. Le, W. Zhao, L. Lee, C. Mackenzie-Kludas, , E

The paper identifies BET inhibitors as potential cardio-protective drugs that block inflammation-induced cardiac dysfunction and SARS-CoV-2 infection in pre-clinical models.

bioRxiv · Aug 23, 2020 · PreprintCell Biology

Oestrogenic vascular effects are diminished by ageing

C. J. Nicholson, M. Sweeney, S. C. Robson, M. J. Taggart

This study shows that ageing and menopause reduce the vasodilatory effects of oestrogen in uterine arteries.

bioRxiv · Feb 14, 2017Physiology