M. Thelen

ACKR5/GPR182 is a scavenger receptor for the atypical chemokine CXCL17, GPR15L and various endogenous peptides

This study identifies GPR182/ACKR5 as a scavenger receptor for CXCL17, GPR15L, and endogenous peptides, revealing distinct binding modes and expanding its ligand repertoire beyond classical chemokines.

T-cell development and activation in humanized mice lacking mouse major histocompatibility complexes

This study shows human T-cell development in humanized mice can occur without mouse MHCs and is enhanced by lentiviral delivery of HLA and cytokines.

Dynamic Phaeodactylum tricornutum Exometabolites Shape Surrounding Bacterial Communities

This study identifies specific exometabolites from the diatom Phaeodactylum tricornutum that influence bacterial community composition in isolation and in a community setting.

Anti-chemokine antibodies after SARS-CoV-2 infection correlate with favorable disease course

The paper finds that anti-chemokine antibodies after SARS-CoV-2 infection correlate with favorable disease outcomes and predict absence of long COVID symptoms.

A pipeline to track unlabeled cells in wide migration chambers using pseudofluorescence

The paper describes a deep learning-based pipeline that converts transmitted light signals from unlabeled cells into pseudofluorescence to improve tracking accuracy and duration in 3D migration chambers.

Small proteins modulate ion channel-like ACD6 to regulate immunity in Arabidopsis thaliana

The paper identifies two small proteins, MHA1 and MHA1L, that modulate ACD6 activity in Arabidopsis thaliana, affecting growth and defense trade-offs through calcium influx regulation.