Author

M. Zand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Ruan· 2 shared B. Alman· 1 shared C.-L. Lin· 1 shared C.-M. Wang· 1 shared D. G. Kirsch· 1 shared D. Sivaraj· 1 shared E. J. Martz· 1 shared H. E. Brighton· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

J. Ruan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loss of the chromatin remodeler, ATRX, promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin receptor binding

S. Bartholf DeWitt, S. Hoskinson Plumlee, H. E. Brighton, D. Sivaraj, E. J. Martz, M. Zand, V. Kumar, M. U. Sheth, W. Floyd, J. Spruance, N. Hawkey, S. Varghese, J. Ruan, D. G. Kirsch, J. Somarelli, , W. C. Eward

This study shows that loss of ATRX in osteosarcoma promotes aggressive tumor features through NF-κB signaling and integrin receptor binding, suggesting new therapeutic targets.

bioRxiv · Apr 22, 2022 · PreprintCancer Biology

Single-cell chromatin profiling reveals demethylation-dependent metabolic vulnerabilities of breast cancer epigenome

M. Kusi, M. Zand, C.-L. Lin, C.-M. Wang, N. D. Lucio, N. B. Kirma, J. Ruan, T. H.- M. Huang, K. Mitsuya

This study uses scATAC-seq to show 2HG enantiomers disrupt DNA and histone demethylation, leading to epigenetic changes in breast cancer cells.

Cell Reports · Jan 1, 2022Peer-reviewedCancer Biology