Author

N. Lue

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. Y. Yu· 2 shared C. Wu· 1 shared E. Falck-Pedersen· 1 shared F. Li· 1 shared H. Ying· 1 shared H. Zheng· 1 shared I. Hwang· 1 shared J. Paik· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

E. Y. Yu

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Author profile →

2 papers

Recent·Most cited

Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

F. Li, Y. Wang, I. Hwang, J.-Y. Janng, L. Zhou, Z. Deng, E. Y. Yu, Y. Cai, C. Wu, Z. Han, Y.-H. Huang, X. Huang, L. Zhang, J. Yao, N. Lue, , H. Zheng

The paper identifies KDM2A as a selective vulnerability in ALT-dependent cancers by showing its role in telomere cluster dissolution through SENP6-mediated SUMO deconjugation.

bioRxiv · Feb 10, 2023 · PreprintCancer Biology

Reciprocal impacts of telomerase activity and tumor cell differentiation in neuroblastoma tumor biology

E. Y. Yu, S. S. Zahid, S. Aloe, E. Falck-Pedersen, X. K. Zhou, N.-K. Cheung, N. Lue

This study shows that telomerase activity and tumor cell differentiation in neuroblastoma are reciprocally linked, with telomerase affecting differentiation and vice versa, impacting tumor biology and immunogenicity.

bioRxiv · May 9, 2021Cancer Biology