Author

N. Seban

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. Srinivasan· 2 shared A. Gingras· 1 shared A. Khan· 1 shared A. Valadez· 1 shared C.-C. Liu· 1 shared F. Lagarrigue· 1 shared K. Ley· 1 shared M. A. Lopez-Ramirez· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

S. Srinivasan

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Author profile →

3 papers

Recent·Most cited

A homeostatic gut-to-brain insulin antagonist restrains neuronally stimulated fat loss

C.-C. Liu, A. Khan, N. Seban, N. Littlejohn, S. Srinivasan

The paper identifies INS-7, an ancestral insulin superfamily peptide in C. elegans, as a gut-to-brain signal that counteracts neuronally driven fat loss during fasting.

bioRxiv · Oct 20, 2023 · PreprintPhysiology

A Feedforward Loop Governs The Relationship Between Lipid Metabolism And Longevity

N. K. Littlejohn, N. Seban, S. Srinivasan

The paper identifies a feedforward loop involving ATGL-1, ATFS-1, and HLH-11/AP4 that links sustained fat oxidation to longevity in C. elegans.

bioRxiv · May 17, 2020Cell Biology

A Rap1 binding site and lipid-dependent helix in talin F1 domain promote integrin activation in tandem

A. Gingras, F. Lagarrigue, M. Cuevas, M. Zorovich, A. Valadez, M. A. Lopez-Ramirez, N. Seban, W. McLaughlin, K. Ley, W. Kiosses, M. Ginsberg

The paper identifies a novel Rap1 binding site in talin1 F1 domain and shows its cooperation with a lipid-dependent amphipathic helix to enable integrin activation.

bioRxiv · Apr 13, 2019Cell Biology