Author

N. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Organism:virus· 1

Frequent Co-Authors

A. Bertoletti· 3 shared A. Chia· 3 shared A. T. Tan· 3 shared K. Kunasegaran· 3 shared N. Le Bert· 3 shared B. Young· 2 shared E. E. Ooi· 2 shared L.-F. Wang· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersImmunology

A. Bertoletti

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Scalable Mesenchymal Stem Cells Enrichment from Bone Marrow Aspirate using Deterministic Lateral Displacement (DLD) Microfluidics Sorting

N. Tan, K. Z. Kwek, K. L. Teo, M. Loberas, J. L. Lee, C. R. Goh, D. Yang, S. Oh, J. Hui, S. Cool, H. Wei Hou, J. Han

This paper develops a microfluidic method to isolate mesenchymal stem cells from bone marrow aspirate more efficiently than centrifugation.

bioRxiv · May 3, 2023 · PreprintBioengineering

Mutations of SARS-CoV-2 variants of concern escaping Spike-specific T cells

N. Le Bert, A. T. Tan, K. Kunasegaran, A. Chia, N. Tan, Q. Chen, S. K. Hang, M. D. Qui, B. S. Chan, J. G. Low, B. Young, K. C. Ng, D. W. S. Chan, D. C. B. Lye, A. Bertoletti

This study examines how mutations in SARS-CoV-2 variants affect Spike-specific T cell responses, finding that some mutations reduce CD8 T cell recognition while overall T cell responses remain largely intact.

bioRxiv · Jan 20, 2022 · PreprintImmunology

Rapid determination of the wide dynamic range of SARS-CoV-2 Spike T cell responses in whole blood of vaccinated and naturally infected

A. T. Tan, J. M. Lim, N. Le Bert, K. Kunasegaran, A. Chia, M. Qui, N. Tan, W. N. Chia, R. Alwis, Y. Ding, E. E. Ooi, L.-F. Wang, M. I. Chen, B. Young, L. Y. Hsu, , A. Bertoletti

This study evaluates a rapid whole blood test for measuring SARS-CoV-2 Spike-specific T cell responses in vaccinated and infected individuals, finding a wide dynamic range independent of neutralizing antibodies.

bioRxiv · Jun 29, 2021 · PreprintImmunology

Different pattern of pre-existing SARS-COV-2 specific T cell immunity in SARS-recovered and uninfected individuals

N. Le Bert, A. T. Tan, K. Kunasegaran, C. Y. L. Tham, M. Hafezi, A. Chia, M. Chng, M. Lin, N. Tan, M. Linster, W. N. Chia, M. I.-C. Chen, L.-F. Wang, E. E. Ooi, S. Kalimuddin, , A. Bertoletti

The paper compares pre-existing SARS-CoV-2 specific T cell immunity in SARS-recovered and uninfected individuals, finding differential T cell immunodominance patterns.

bioRxiv · May 26, 2020Immunology