Author

N. Xue

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. Nyati· 1 shared B. Zhu· 1 shared C. Luan· 1 shared C. Yi· 1 shared D. Li· 1 shared D. S. Navaratnam· 1 shared D. Zhang· 1 shared G. Ru· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

A. Nyati

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2 papers

Recent·Most cited

Engineering precise adenine base editor with infinitesimal rates of bystander mutations and off-target editing

L. Chen, S. Zhang, N. Xue, M. Hong, X. Zhang, D. Zhang, J. Yang, S. Bai, Y. Huang, H. Meng, H. Wu, C. Luan, B. Zhu, G. Ru, M. Liu, , D. Li

This paper engineers a precise adenine base editor, ABE9, with reduced bystander mutations and off-target effects, enabling efficient and accurate A-to-G editing in mouse and rat embryos.

bioRxiv · Aug 12, 2022 · PreprintBioengineering

Calcium induced calcium release in proximity to hair cell BK channels revealed by PKA activation

J. Bai, N. Xue, O. Lawal, A. Nyati, J. Santos-Sacchi, D. S. Navaratnam

The paper shows that PKA activation enhances BK currents in chicken hair cells by increasing Ca2+ concentrations via CICR near BK channels.

bioRxiv · Dec 30, 2019Physiology