Author

O. Koczy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. J. Counsell· 1 shared A. Kumar· 1 shared B. B. Khadgi· 1 shared B. M. Evers· 1 shared C. V. Robinson· 1 shared C. Xing· 1 shared C. Zhang· 1 shared D. J. Sherratt· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBiochemistry

A. J. Counsell

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Author profile →

3 papers

Recent·Most cited

Cancer mutations rewire the RNA methylation specificity of METTL3-METTL14

C. Zhang, L. Tunes, M.-H. Hsieh, P. Wang, A. Kumar, B. B. Khadgi, Y.-Y. Yang, K. A. Doxtader, E. Herrell, O. Koczy, R. Setlem, X. Zhang, B. M. Evers, Y. Wang, C. Xing, , Y. Nam

The paper shows that a cancer mutation in METTL14 changes RNA methylation specificity, promoting oncogenesis by altering gene expression without increasing global m6A levels.

bioRxiv · Mar 16, 2023 · PreprintBiochemistry

A Recombinant Approach For Stapled Peptide Discovery YieldsInhibitors of the RAD51 Recombinase

T. Pantelejevs, P. Zuazua-Villar, O. Koczy, A. J. Counsell, S. J. Walsh, N. S. Robertson, D. R. Spring, J. A. Downs, M. Hyvonen

This paper describes a recombinant approach for stapled peptide discovery and evaluates its effectiveness as inhibitors of the RAD51 recombinase.

bioRxiv · Feb 24, 2023Biochemistry

Dynamic architecture of the Escherichia coli structural maintenance of chromosomes (SMC) complex, MukBEF

L. K. Arciszewska, K. V. Rajasekar, M. Tang, R. Baker, K. Zawadzka, O. Koczy, F. Wagner, J. R. Bolla, C. V. Robinson, D. J. Sherratt

The paper examines how nucleotide binding and ATP hydrolysis affect the architecture of the Escherichia coli SMC complex MukBEF.

bioRxiv · Feb 12, 2019Biochemistry