Author

R. Setlem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Kumar· 1 shared B. B. Khadgi· 1 shared B. M. Evers· 1 shared C. V. Camacho· 1 shared C. Xing· 1 shared C. Zhang· 1 shared D. Kim· 1 shared E. Herrell· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Kumar

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer mutations rewire the RNA methylation specificity of METTL3-METTL14

C. Zhang, L. Tunes, M.-H. Hsieh, P. Wang, A. Kumar, B. B. Khadgi, Y.-Y. Yang, K. A. Doxtader, E. Herrell, O. Koczy, R. Setlem, X. Zhang, B. M. Evers, Y. Wang, C. Xing, , Y. Nam

The paper shows that a cancer mutation in METTL14 changes RNA methylation specificity, promoting oncogenesis by altering gene expression without increasing global m6A levels.

bioRxiv · Mar 16, 2023 · PreprintBiochemistry

Functional Characterization of lncRNA152 as an Angiogenesis-Inhibiting Tumor Suppressor in Triple-Negative Breast Cancers

D. Kim, S. Gadad, R. Setlem, K. Kim, S. Malladi, T. Hou, T. Nandu, C. V. Camacho, W. L. Kraus

This study identifies lncRNA152 as an angiogenesis-inhibiting tumor suppressor in TNBC that upregulates RBM47, reducing cancer aggressiveness.

bioRxiv · Feb 9, 2022Cancer Biology