O. Yurieva

This study shows that the yeast origin recognition complex can bind nucleosomes and license replication origins without requiring a consensus DNA sequence, suggesting this mechanism is conserved across eukaryotes.

The paper shows how DNA polymerase stability and exchange dynamics in the yeast replisome are tuned by local concentrations, enabling efficient replication and adaptation to genomic challenges.

This study shows Mcm10 enables CMG helicase to bypass DNA blocks on the non-tracking strand by isomerizing the CMG-DNA complex.