Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
C. Schmidt, S. Cohen, B. L. Gudenas…·B. Schwer
This study shows PRDM6 represses chromatin accessibility and alters gene expression in neuroepithelial stem cells, promoting medulloblastoma but not sufficient to drive Group 4 medulloblastoma alone.
K. Okonechnikov, P. Joshi, M. Sepp…·S. M. Pfister
The paper maps the cellular origins of three common pediatric brain tumors using a single-nucleus atlas and transcriptome data, identifying lineage-specific origins and potential therapeutic targets.
A. Inoue, L. J. Janke, B. L. Gudenas…·X. Cao
This paper develops a genetic mouse model of MPNST that closely mimics human tumors in genetics, histology, and transcriptome.
C. He, K. Xu, X. Zhu…·S. J. Baker
The paper establishes patient-derived orthotopic xenograft models and cell lines from pediatric high-grade glioma that replicate histopathology, molecular signatures, and drug response, providing a resource for research.
L. M. Kutscher, K. Okonechnikov, N. V. Batora…·D. Kawauchi
This study shows that loss of BCOR in SHH-medulloblastoma accelerates tumor formation by disrupting the BCOR-PRC1.1 complex and increasing Igf2 expression.