P. Bao

De novo multi-mechanism antimicrobial peptide design via multimodal deep learning

This paper introduces M3-CAD, a deep learning pipeline for designing multi-mechanism antimicrobial peptides to combat multidrug-resistant organisms, showing effectiveness in a skin wound infection model.

A thermodynamic chemical reaction network drove autocatalytic prebiotic peptides formation

This study demonstrates that a thermodynamic chemical reaction network involving Sammox could drive autocatalytic peptide formation under hydrothermal conditions, with peptides exhibiting reversible catalytic properties.