Author

P. Daniel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. Filiz· 2 shared T. Mantamadiotis· 2 shared A. H. Kaye· 1 shared A. M. Douglas· 1 shared A. Mannan· 1 shared A. Susor· 1 shared B. Nixon· 1 shared C. Koschmann· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPathology

G. Filiz

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Author profile →

4 papers

Recent·Most cited

Ribosome transfer via tunnelling nanotubes rescues protein synthesis in pancreatic cancer cells

S. Martinkova, D. Jansova, J. Vorel, L. J. Lamacova, P. Daniel, M. Hudec, M. Bodo, J. Hajer, A. Susor, J. Trnka

This study shows pancreatic cancer cells use tunnelling nanotubes to transfer ribosomes and mRNAs, restoring protein synthesis in cells with impaired translation.

Cell Communication and Signaling · Mar 7, 2026Peer-reviewedCancer Biology

PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma

R. J. Duchatel, E. R. Jackson, S. G. Parackal, C. Sun, P. Daniel, A. Mannan, I. J. Findlay, D. Staudt, Z. P. Germon, S. Laternser, D. Kiltschewskij, P. S. Kearney, M. F. B. Jamaluddin, A. M. Douglas, T. Beitaki, , M. D. Dun

This study identifies PI3K/mTOR as a targetable genetic dependency in DIPG and demonstrates that combining paxalisib with metformin improves survival in xenograft models.

bioRxiv · Apr 17, 2023Cancer Biology

Intratumoral MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissuecorrelates with selective CREB signaling and specific functional gene signatures

P. Daniel, G. Filiz, M. Tymms, R. Ramsay, A. H. Kaye, S. Stylli, T. Mantamadiotis

The paper identifies intratumoral heterogeneity in glioblastoma by analyzing MAPK and PI3K pathway activation and their correlation with CREB signaling and gene signatures.

bioRxiv · Apr 20, 2018Pathology

PI3K Activation In Neural Stem Cells Drives Tumorigenesis Which Can Be Suppressed By Targeting CREB

P. Daniel, G. Filiz, D. Brown, M. Christie, P. Waring, Y. Zhang, J. Haynes, C. Pouton, D. Flanagan, E. Vincan, T. Johns, K. Montgomery, W. Phillips, T. Mantamadiotis

This study shows that PI3K pathway activation in neural stem cells initiates tumorigenesis, and targeting CREB reduces tumor growth in a mouse model of high-grade glioma.

bioRxiv · May 30, 2017Cancer Biology