Author

W. Phillips

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. E. Yesilkanal· 1 shared A. Klein· 1 shared A. Muir· 1 shared A. Sethi· 1 shared A. Thakur· 1 shared A. Yu· 1 shared C. Pouton· 1 shared D. Brown· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. E. Yesilkanal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell invasive amyloid assemblies from SARS-CoV-2 peptides can form multiple polymorphs with varying neurotoxicity

O. Sanislav, R. Tetaj, J. Ratcliffe, W. Phillips, A. Klein, A. Sethi, J. Zhou, R. Mezzenga, S. Saxer, M. Charnley, S. J. Annesley, N. Reynolds

This study investigates how SARS-CoV-2 peptides form amyloid assemblies with varying neurotoxicity and polymorphic structures, showing that aggregation conditions influence toxicity and cellular uptake.

bioRxiv · May 16, 2024Biophysics

HYENA detects oncogenes activated by distal enhancers in cancer

A. Yu, A. E. Yesilkanal, A. Thakur, F. Wang, Y. Yang, W. Phillips, X. Wu, A. Muir, X. He, F. Spitz, L. Yang

HYENA identifies oncogenes, including non-coding genes, activated by enhancer hijacking in cancer using whole-genome and transcriptome sequencing data.

bioRxiv · Jan 9, 2023Cancer Biology

Characterization of gene repression by designed transcription activator-like effector dimer proteins

N. Becker, J. Peters, T. Schwab, W. Phillips, J. Wallace, K. Clark, L. J. Maher

The paper quantitatively characterizes gene repression in E. coli using designed TALED proteins and compares them to natural lac repressor loops.

Biophysical Journal · Nov 1, 2020Peer-reviewedBiophysics

PI3K Activation In Neural Stem Cells Drives Tumorigenesis Which Can Be Suppressed By Targeting CREB

P. Daniel, G. Filiz, D. Brown, M. Christie, P. Waring, Y. Zhang, J. Haynes, C. Pouton, D. Flanagan, E. Vincan, T. Johns, K. Montgomery, W. Phillips, T. Mantamadiotis

This study shows that PI3K pathway activation in neural stem cells initiates tumorigenesis, and targeting CREB reduces tumor growth in a mouse model of high-grade glioma.

bioRxiv · May 30, 2017Cancer Biology