Author

P. Pompach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

S. Zoll· 2 shared A. Dhillon· 1 shared A. Kadek· 1 shared A. Kadlecova· 1 shared A. N. Volkov· 1 shared A. Zeck· 1 shared B. D. Persson· 1 shared C. Uetrecht· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

S. Zoll

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A selective alternative pathway complement inhibitor for treatment of paroxysmal nocturnal hemoglobinuria

H. Sülzen, H. Tulmin, M. Hajek, J. Cermak, A. Kadlecova, P. Pompach, J. Votrubova, M. Zoltner, S. Zoll

This paper introduces SH-01, a novel recombinant protein that selectively inhibits the complement alternative pathway, showing efficacy in preventing PNH-related erythrocyte lysis and reduced infection risk compared to current treatments.

bioRxiv · Jun 23, 2024 · PreprintImmunology

Structural Insights into the Interaction Between Adenovirus C5 Hexon and Human Lactoferrin

A. Dhillon, B. D. Persson, A. N. Volkov, H. Sulzen, A. Kadek, P. Pompach, S. Kereiche, M. Lepsik, K. Danskog, C. Uetrecht, N. Arnberg, S. Zoll

This study presents cryo-EM structures of HAdV-5C hexon and its complex with human lactoferrin, revealing molecular interactions critical for viral entry.

bioRxiv · Oct 9, 2023Biochemistry

Development of a PNGase Rc column for online deglycosylation of complex glycoproteins during HDX-MS

T. O. T. Lambert, M. Gramlich, L. S. Stutzke, L. Smith, D. Deng, P. D. Kaiser, U. Rothbauer, J. L. Benesch, C. Wagner, M. Koenig, P. Pompach, P. Novak, A. Zeck, K. D. Rand

The paper develops a PNGase Rc column for online deglycosylation during HDX-MS, enabling efficient analysis of glycoproteins and mapping of mAb binding epitopes.

bioRxiv · Jul 28, 2023Biochemistry