Author

R. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Plant Biology· 2 Biophysics· 1 Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Assay:proteomics· 3 Assay:electronic health records· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:plant (other)· 2

Frequent Co-Authors

G. S. Demirer· 2 shared H. Zhang· 2 shared M. P. Landry· 2 shared M. Prakash· 2 shared A. Davydov· 1 shared A. J. Aditham· 1 shared A. Siryaporn· 1 shared A. Tang· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersPlant Biology

G. S. Demirer

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

The great divide: rhamnolipids mediate separation between P. aeruginosa and S. aureus

J.-L. Bru, S. J. Kasallis, R. Chang, Q. Zhuo, J. Nguyen, P. Pham, E. Warren, K. Whiteson, N. M. Hoyland-Kroghsbo, D. H. Limoli, A. Siryaporn

This study shows that rhamnolipids mediate physical separation between P. aeruginosa and S. aureus, enabling coexistence through surfactant flow deflection.

bioRxiv · Jun 23, 2023 · PreprintMicrobiology

Energetics of the Microsporidian Polar Tube Invasion Machinery

R. Chang, A. Davydov, P. Jaroenlak, B. Budaitis, D. C. Ekiert, G. Bhabha, M. Prakash

This study analyzes the biophysical energy requirements of microsporidian polar tube ejection using 3D imaging and theoretical modeling.

bioRxiv · Jan 17, 2023Biophysics

Novel inhibitors against COVID-19 main protease suppressed viral infection

V. Ramachandran, Y. Liu, Q. He, A. Tang, P. Ronaldson, D. Schenten, R. Chang

This study identifies novel small-molecule inhibitors of SARS-CoV-2 main protease that suppress viral replication in human cells.

bioRxiv · Nov 5, 2022 · PreprintPathology

Topological damping in an ultrafast giant cell

R. Chang, M. Prakash

The paper investigates how Spirostomum ambiguum dissipates energy during ultrafast contractions by discovering a novel RER-vacuole entangled meshwork and modeling its mechanical properties as topological damping.

bioRxiv · Dec 13, 2021 · PreprintCell Biology

Effects of carbon-based additive and ventilation rate on nitrogen loss and microbial community during chicken manure composting

R. Chang, Y. Li, Q. Chen, X. Gong, Z. Qi

The paper investigates how carbon-based additives and ventilation rates affect nitrogen loss and microbial communities in chicken manure composting, finding that woody peat reduces nitrogen loss more effectively than other additives.

bioRxiv · Feb 19, 2020Bioengineering

Carbon Nanocarriers Deliver siRNA to Intact Plant Cells for Efficient Gene Knockdown

G. S. Demirer, H. Zhang, N. S. Goh, R. L. Pinals, R. Chang, M. P. Landry

This study develops nanotube-based delivery of siRNA to plant cells, achieving efficient gene knockdown by overcoming cell wall barriers and nuclease degradation.

bioRxiv · Dec 12, 2019 · PreprintPlant Biology

DNA-scaffolded biomaterials enable modular and tunable control of cell-based cancer immunotherapies

X. Huang, J. Z. Williams, R. Chang, Z. Li, E. Gai, D. M. Patterson, W. Yu, W. A. Lim, T. A. Desai

The paper develops a biomaterial platform to control immune cell activity by modulating protein ratios on biodegradable particles, enhancing cancer immunotherapy efficacy and safety.

bioRxiv · Mar 23, 2019 · PreprintBioengineering

High Aspect Ratio Nanomaterials Enable Delivery of Functional Genetic Material Without DNA Integration in Mature Plants

G. S. Demirer, H. Zhang, J. Matos, N. Goh, F. J. Cunningham, Y. Sung, R. Chang, A. J. Aditham, L. Chio, M.-J. Cho, B. Staskawicz, M. P. Landry

This study shows high aspect ratio nanomaterials can deliver functional genetic material to plants without DNA integration, using multiple species and demonstrating siRNA gene silencing.

bioRxiv · Aug 2, 2018Plant Biology