Author

R. Dummer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

M. Levesque· 3 shared A. Aloia· 1 shared A. Bileck· 1 shared A. Dzung· 1 shared A. Grimm· 1 shared A. H. Shain· 1 shared A. Hajnal· 1 shared A. Harari· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCancer Biology

M. Levesque

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The genetic evolution of acral melanoma

M. Wang, S. Fukushima, Y.-S. Sheen, E. Ramelyte, N. Cruz Pacheco, C. Shi, S. Liu, I. Banik, J. D. Aquino, M. Sangueza Acosta, M. Levesque, R. Dummer, J.-Y. Liau, C.-Y. Chu, A. H. Shain, , B. C. Bastian

This study analyzes exome sequencing data from acral melanoma patients to identify distinct genetic evolution patterns compared to sun-exposed melanomas.

bioRxiv · Oct 18, 2023Cancer Biology

Standardization of suspension and imaging mass cytometry readouts for clinical decision making

R. Casanova, S. Xu, S. Sivapatham, A. Jacobs, S. Engler, Tumor Profiler Consortium, M. P. Levesque, R. Dummer, B. Bodenmiller, S. Chevrier

This study standardizes suspension and imaging mass cytometry measurements to improve clinical reproducibility and provide oncologists with tumor biology insights.

bioRxiv · Mar 19, 2023 · PreprintCancer Biology

Tumor Microenvironment Cellular Crosstalk Predicts Response to Adoptive TIL Therapy in Melanoma

D. Barras, E. Ghisoni, J. Chiffelle, A. Orcurto, J. Dagher, N. Fahr, F. Benedetti, I. Crespo, S. Zimmermann, R. Duran, M. Imbimbo, M. Ochoa De Olza, B. Navarro, K. Homiscko, S. Bobisse, , G. Coukos

This study identifies CD8+ TIL-myeloid cell networks as predictors of response to adoptive TIL therapy in melanoma using single-cell RNA-seq and spatial proteomic analyses.

bioRxiv · Dec 23, 2022 · PreprintImmunology

ROS induction as a strategy to target persister cancer cells with low metabolic activity in NRAS mutated melanoma

O. M. Eichhoff, C. I. Stoffel, J. Kaesler, L. Briker, P. Turko, G. Karsai, N. Zila, V. Paulitschke, P. F. Cheng, A. Leitner, A. Bileck, N. Zamboni, A. Irmisch, Z. Balazs, A. Tastanova, , M. Levesque

The paper identifies ROS induction as a strategy to target MEK-inhibitor resistant NRAS-mutated melanoma cells by exploiting their quiescent metabolic state and elevated baseline ROS levels.

bioRxiv · Oct 19, 2022 · PreprintCancer Biology

A DNA Replication-Independent Function of the pre-Replication Complex during Cell Invasion in C. elegans

E. Lattmann, T. Deng, M. Walser, P. Widmer, C. Rexha-Lambert, V. Prasad, O. Eichhoff, M. Daube, R. Dummer, M. Levesque, A. Hajnal

The paper identifies the pre-RC complex as a regulator of cell invasion in C. elegans, independent of its role in DNA replication.

bioRxiv · Jun 10, 2021 · PreprintCell Biology