R. G. Efremov

This study presents the first cryo-EM structure of an invertebrate nACh-like receptor, revealing conformational changes induced by sterol derivative binding and unique structural features.

This paper develops a time-resolved cryo-EM technique with 5 ms resolution, enabling visualization of transient protein conformations in the GroEL:GroES chaperonin complex.

This paper investigates how oncogenic mutations in the transmembrane domain of RTKs promote tetramerization and ligand-independent activation through structural and dynamic changes.

The paper uses atomic force microscopy to study the stepwise formation of a DNA transposition complex involved in antibiotic resistance dissemination.

This study connects molecular dynamics simulations of Lge11-80 with in vitro condensate behavior to derive a framework describing condensate architecture based on protein valency and compactness.

TCRen predicts TCR recognition of unseen epitopes using residue-level pairwise statistical potential from TCR-peptide contacts in crystal structures.

The paper presents the cryo-EM structure of E. coli complex I reconstituted in lipid nanodiscs, revealing an uncoupled conformation and proposing a new coupling mechanism.