Author

R. Immareddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:non-human primate· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. K. A. Van Rompay· 4 shared J. K. Watanabe· 2 shared J. L. Usachenko· 2 shared J. R. Reader· 2 shared J. Usachenko· 2 shared J. W. Roh· 2 shared J. Watanabe· 2 shared K. J. Olstad· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersImmunology

K. K. A. Van Rompay

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4 papers

Recent·Most cited

A Virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in Non-Human Primates

A. Fowler, K. K. A. Van Rompay, M. Sampson, J. Leo, J. K. Watanabe, J. L. Usachenko, R. Immareddy, D. M. Lovato, J. T. Schiller, A. T. Remaley, B. Chackerian

A bivalent PCSK9 vaccine using virus-like particles reduces LDL-cholesterol in non-human primates without statins, showing vaccine efficacy in cholesterol management.

bioRxiv · May 15, 2023Immunology

Distinct upper airway epithelium interferon-stimulated and profibrotic gene expression between adult and infant rhesus macaques infected with SARS-CoV-2

S. N. Langel, C. Garrido, C. Phan, T. Travieso, T. DeMarco, Z.-M. Ma, J. R. Reader, K. J. Olstad, R. L. Sammak, Y. Shaan Lakshmanappa, J. W. Roh, J. Watanabe, J. Usachenko, R. Immareddy, R. E. Pollard, , M. Blasi

This study compares SARS-CoV-2 infection effects in adult and infant rhesus macaques, finding distinct interferon-stimulated and profibrotic gene expression patterns in upper airway epithelium.

bioRxiv · Feb 12, 2022Immunology

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

K. K. A. Van Rompay, K. J. Olstad, R. L. Sammak, J. Dutra, J. K. Watanabe, J. L. Usachenko, R. Immareddy, J. W. Roh, A. Verma, Y. Shaan Lakshmanappa, B. Schmidt, C. Di Germanio, N. Rizvi, M. Stone, G. Simmons, , J. R. Reader

This study treats SARS-CoV-2 infected macaques with high-titer convalescent plasma, showing reduced lung inflammation without affecting virus replication.

bioRxiv · Sep 1, 2021 · PreprintImmunology

A Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by Zika Virus in Macaques

K. K. A. Van Rompay, L. L. Coffey, T. Kapoor, A. Gazumyan, R. I. Keesler, A. Jurado, A. Peace, M. Agudelo, J. Watanabe, J. Usachenko, A. Singapuri, R. Immareddy, A. Ardeshir, J. B. Stuart, S. Bournazos, , D. F. Robbiani

This study shows that two Fc-modified monoclonal antibodies limit fetal neurologic damage and vertical transmission of ZIKV in pregnant macaques.

bioRxiv · Jan 31, 2020Immunology