K. K. A. Van Rompay

A bivalent PCSK9 vaccine using virus-like particles reduces LDL-cholesterol in non-human primates without statins, showing vaccine efficacy in cholesterol management.

This study identifies inducible bronchus-associated lymphoid tissue in SARS-CoV-2 infected rhesus macaques, suggesting local immunity plays a role in infection.

This study investigates ZIKV persistence in male macaque reproductive tissues, finding prolonged viral presence in germ and epithelial cells and potential impacts on fertility.

This study tests a vaccine regimen in infant rhesus macaques, finding that Env-specific antibodies with Fc effector functions do not prevent oral SHIV infection.

This study compares SARS-CoV-2 infection effects in adult and infant rhesus macaques, finding distinct interferon-stimulated and profibrotic gene expression patterns in upper airway epithelium.

This study treats SARS-CoV-2 infected macaques with high-titer convalescent plasma, showing reduced lung inflammation without affecting virus replication.

This study evaluates two SARS-CoV-2 vaccines in infant rhesus macaques, finding both induce durable antibody and T cell responses without adverse effects.

This paper identifies a ZIKV mutation, M1404I, that enhances fetal infection in mice but reduces viral fitness and transmissibility in nonpregnant macaques and mosquitoes.

The paper sequenced genomes of Pneumocystis species from different mammals to study host specificity and evolutionary adaptations, revealing insights into the emergence of the human pathogen P. jirovecii.

This study shows that two Fc-modified monoclonal antibodies limit fetal neurologic damage and vertical transmission of ZIKV in pregnant macaques.

This paper develops an infant rhesus macaque model of SHIV infection and analytical treatment interruption to study viral rebound and identify biomarkers for pediatric HIV functional cure strategies.

This study compares HIV-specific antibody kinetics in infant and adult rhesus macaques infected with SHIV, finding similar antibody responses despite differences in Tfh and germinal center B cell dynamics.