Author

R. Lo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

T. B. K. Le· 2 shared A. Badrinarayanan· 1 shared A. Joseph· 1 shared A. Noy· 1 shared A. S. B. Jalal· 1 shared B. Raman· 1 shared C. E. Stevenson· 1 shared D. M. Lawson· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

T. B. K. Le

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Requirement for specific bacterial genome maintenance pathways in repair of C8-linked pyrrolobenzodiazepine (PBD) bi-aryl monomer-mediated DNA damage

A. Joseph, K. Nahar, S. Daw, M. Hasan, R. Lo, T. B. K. Le, K. Rahman, A. Badrinarayanan

This study investigates how C8-linked PBD bi-aryl monomers cause DNA damage in Caulobacter crescentus and identifies the repair mechanisms required for survival.

bioRxiv · Jun 10, 2022 · PreprintMicrobiology

Diversification of DNA-binding specificity via permissive and specificity-switching mutations in the ParB/Noc protein family

A. S. B. Jalal, N. T. Tran, C. E. Stevenson, E. W. Chan, R. Lo, X. Tan, A. Noy, D. M. Lawson, T. B. K. Le

This study investigates how DNA-binding specificity diversifies in ParB and Noc proteins by identifying key residues and mutational paths that reprogram specificity.

bioRxiv · Jun 24, 2020Microbiology

An Arf/Rab cascade controls the growth and invasiveness of glioblastoma

G. Kulasekaran, M. Chaineau, V. E. Piscapo, F. Verginelli, M. Fotouhi, M. Girard, Y. Tang, R. Dali, R. Lo, S. Stifani, P. S. McPherson

This study shows that loss of Rab35 or Arf5 in glioblastoma cells increases tumor growth and invasiveness by activating the epidermal growth factor receptor and upregulating SPOCD1.

bioRxiv · Apr 30, 2020Cancer Biology

Explosive sensing with insect-based biorobots

D. Saha, D. Mehta, E. Altan, R. Chandak, M. Traner, R. Lo, P. Gupta, S. Singamaneni, S. Chakrabartty, B. Raman

This study demonstrates a biorobotic chemical sensing system using locust brain signals to detect and distinguish explosive vapors rapidly.

bioRxiv · Feb 10, 2020Bioengineering

Rho-mediated gene transcription promotes BRAF inhibitor resistance in de-differentiated melanoma cells

S. A. Misek, K. M. Appleton, T. S. Dexheimer, E. M. Lisabeth, R. Lo, S. D. Larsen, K. Gallo, R. R. Neubig

This study identifies RhoA-mediated gene transcription as a mechanism of BRAF inhibitor resistance in melanoma, showing that targeting this pathway can re-sensitize resistant cells to vemurafenib.

bioRxiv · Mar 31, 2019 · PreprintCancer Biology