D. Mehta

B4 Raf-like MAPKKK RAF24 regulates Arabidopsis thaliana flowering time through HISTONE MONO-UBIQUITINATION 2

This study identifies RAF24 as a regulator of Arabidopsis flowering time through its effect on HUB2 phosphorylation and ubiquitin ligase activity.

Endothelial ERG programs neutrophil transcriptome for sustained anti-inflammatory vascular niche

This study shows that endothelial ERG regulates neutrophil transcriptome to create an anti-inflammatory vascular niche, preventing excessive inflammation.

Silversol (a colloidal nanosilver formulation) inhibits growth of antibiotic-resistant Staphylococcus aureus by disrupting its physiology in multiple ways

Silversol inhibits antibiotic-resistant Staphylococcus aureus growth by disrupting multiple physiological processes and altering gene expression related to virulence and metal homeostasis.

Matrimeres are systemic nanoscale mediators of tissue integrity and function

The paper identifies matrimeres as nanoscale mediators of tissue integrity, showing they can restore vascular integrity after injury and are reconstituted from fibronectin, DNA, and acidic conditions.

RGS2 is an innate immune checkpoint for TLR4 and Gαq-mediated IFNγ generation and lung injury

This study shows RGS2 limits IFNγ production in alveolar macrophages by inhibiting TLR4-Gαq signaling, reducing lung injury in mice and correlating with ARDS patient data.

Identifying molecular targets of a colloidal nanosilver formulation (Silversol) in multidrug resistant Pseudomonas aeruginosa

The paper investigates the molecular targets of Silversol, a colloidal nanosilver formulation, in multidrug-resistant P. aeruginosa, identifying key genes involved in nitrogen metabolism and denitrification as potential targets.

Twilight length alters growth, flowering time, and clock function in Arabidopsis via LHY/CCA1

This study shows that twilight length affects Arabidopsis growth, flowering time, and circadian clock function through the LHY/CCA1 pathway.

Tension sensing by FAK governs nuclear mechanotransduction, endothelial transcriptome and fate

This study shows that FAK-mediated tension sensing in endothelial cells regulates nuclear mechanotransduction, transcriptome, and cell fate, crucial for maintaining a restrictive endothelial barrier.

Integrated Systems-Level Proteomics and Metabolomics Reveals the Diel Molecular Landscape of Diverse Kale Cultivars

The paper analyzes diel proteome and metabolome changes in nine kale cultivars to understand their molecular landscape under vertical farming conditions.

Multi-omic analysis of the Arabidopsis clock activator mutant rve 4 6 8 reveals connections to carbohydrate metabolism and proteasome regulation

This study uses multi-omics analysis to show that RVE8-like proteins in Arabidopsis affect carbohydrate metabolism and proteasome activity, leading to altered plant growth and physiology.

Computer-Vision Stabilized Intravital Imaging Reveals Lung Capillary Neutrophil Dynamics Crucial for Lung Host-Defense Function

This study uses CASTii to analyze lung capillary neutrophil dynamics, revealing their role in host defense and response to infection.

Quantitative proteome and PTMome analysis of Arabidopsis thaliana root responses to persistent osmotic and salinity stress.

This study analyzes proteome and PTMome changes in Arabidopsis roots under osmotic and salt stress, revealing distinct regulatory mechanisms across different proteome levels.

Library-free BoxCarDIA solves the missing value problem in label-free quantitative proteomics

This paper introduces BoxCarDIA, a library-free method for label-free quantitative proteomics that improves protein quantification and addresses the missing-value problem in plant proteomics.

Phosphate and phosphite differentially impact the proteome and phosphoproteome of Arabidopsis suspension cell cultures

The paper compares proteome and phosphoproteome responses of Arabidopsis cells to phosphate and phosphite resupply, identifying phosphorylation changes linked to phosphorus nutrition.

Explosive sensing with insect-based biorobots

This study demonstrates a biorobotic chemical sensing system using locust brain signals to detect and distinguish explosive vapors rapidly.

Cooperation only for high rewards - a solvable task-based study on free-ranging dogs

This study investigates cooperation and social tolerance in free-ranging dogs through three tasks with varying food rewards, finding context-dependent cooperation and food sharing.

Non-coding RNAs control metabolic state in mycobacteria

The paper identifies a family of non-coding RNAs in actinobacteria that regulate metabolic state by recruiting ANTAR proteins to target transcripts, promoting reductive metabolism in mycobacteria.

CRISPR-Cas9 interference in cassava linked to the evolution of editing-resistant geminiviruses

The paper shows that CRISPR-Cas9 editing in cassava leads to the evolution of editing-resistant geminiviruses in 33-48% of cases.

Early transcriptome analysis of the brown streak virus-cassava pathosystem provides molecular insights into virus susceptibility and resistance

This study analyzes the transcriptome of cassava infected with brown streak viruses to identify molecular mechanisms of susceptibility and resistance.