R. O'Connell

The paper develops a CRISPR-Cas9 and URA3-based marker recycling system to efficiently knock out multiple genes in Colletotrichum higginsianum, demonstrating its effectiveness in analyzing virulence factors.

This study shows that Clec12a limits inflammation and prevents the expansion of a harmful commensal bacteria, Faecalibaculum rodentium, by enhancing macrophage phagocytosis.

This study identifies distinct metabolomic profiles in synovial fluid associated with knee injury types and patient sex, suggesting metabolic differences linked to post-traumatic osteoarthritis development.

This study identifies eHsp90 as a marker of T cell activation, showing its upregulation in autoimmune diseases and demonstrating the efficacy of an inhibitor in delaying disease progression.

This paper identifies a 28-amino-acid region in Arc critical for oligomerization and virus-like capsid formation, showing that exogenous RNA enhances assembly.