A. Fuller

A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

The paper investigates the cellular response to mitochondrial dysfunction in mtDNA maintenance disorders using imaging mass cytometry, finding complex-specific upregulation and proteostasis activation.

Can a flower color ancestral polymorphism transcend speciation?

The paper investigates shared blue-orange petal color polymorphisms in two closely related species, suggesting an ancestral polymorphism that may have transcended speciation.

Estimates of Fall-run Chinook Salmon Escapement in Two San Joaquin River Tributaries from Device-based and Survey-based Methods

The paper compares carcass surveys and weir-based counting methods for estimating fall-run Chinook Salmon escapement in two rivers, finding weir estimates consistently higher and highly correlated with survey estimates.

Metagenomics uncovers dietary adaptations for chitin digestion in the gut microbiota of convergent myrmecophagous mammals

The paper uses metagenomics to identify chitinolytic bacteria in the gut microbiota of myrmecophagous mammals, revealing convergent adaptations for chitin digestion across species.

CXCR2 inhibition enables NASH-HCC immunotherapy

This study shows that combining CXCR2 inhibition with anti-PD1 therapy enhances immunotherapy response in NASH-HCC by reprogramming tumor-associated neutrophils.

An ex vivo human bone marrow milieu identifies CDH2 as a driver of niche-mediated treatment resistance in leukaemia

This study identifies CDH2 as a driver of niche-mediated treatment resistance in leukemia and shows that ADH-1 can effectively target this resistance in preclinical models.

Magnitude and kinetics of T cell and antibody responses during H1N1pdm09 infection in outbred and inbred Babraham pigs

This study compares T cell and antibody responses to H1N1pdm09 infection in inbred and outbred pigs, showing similar immune responses despite differences in genetic background.

Infrared thermography cannot be used to approximate core body temperature in wild primates

This study shows that infrared thermography cannot reliably approximate core body temperature in wild vervet monkeys when local climate effects are controlled.

A cell atlas of human thymic development defines T cell repertoire formation

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.