Author

G. Wells

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 3 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Assay:metagenomics· 4 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

Y. Wang· 3 shared A. Rosenthal· 2 shared F. Sabba· 2 shared F. Yang· 2 shared H. Zhang· 2 shared J. Kozak· 2 shared P. Roots· 2 shared S. A. Harris· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

Y. Wang

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Detection of Mycobacterium tuberculosis in human tissue via RNA in situ hybridization

k. Nargan, T. Naidoo, M. Msimang, S. Nadeem, G. Wells, R. L. Hunter, A. Hutton, K. Lumamba, J. N. Glasgow, P. V. Benson, A. J. Steyn

This paper uses RNA in situ hybridization to detect Mycobacterium tuberculosis mRNA in human tissue, identifying Mtb in ZN-negative samples and revealing two distinct Mtb populations.

bioRxiv · Oct 4, 2023 · PreprintMicrobiology

Meta-omic profiling reveals ubiquity of genes encoding for the high value nitrogen rich biopolymer cyanophycin in activated sludge microbiomes

M. Farmer, R. Raj, W. Tarpeh, K. Tyo, G. Wells

The paper identifies the ubiquity of the cyanophycin synthesis gene cphA in activated sludge microbiomes, suggesting potential for simultaneous nitrogen and phosphorus recovery.

bioRxiv · Aug 22, 2023Ecology

Intelligent Resolution: Integrating Cryo-EM with AI-driven Multi-resolution Simulations to Observe the SARS-CoV-2 Replication-Transcription Machinery in Action

A. Trifan, D. Gorgun, Z. Li, A. Brace, M. Zvyagin, H. Ma, A. R. Clyde, D. A. Clark, M. Salim, D. Hardy, T. Burnley, L. Huang, J. McCalpin, M. Emani, H. Yoo, , A. Ramanathan

This study develops an AI-driven multi-resolution simulation workflow to study SARS-CoV-2 RTC dynamics, combining cryo-EM with mesoscale simulations and AI methods.

bioRxiv · Oct 9, 2021 · PreprintBiophysics

Modelling the active SARS-CoV-2 helicase complex as a basis for structure-based inhibitor design

D. Berta, M. Badaoui, P. J. Buigues, S. A. Martino, A. Pisliakov, N. Elghobashi-Meinhardt, G. Wells, S. A. Harris, E. Frezza, E. Rosta

This study models the active SARS-CoV-2 helicase complex to provide structural insights for inhibitor design.

bioRxiv · Nov 3, 2020Biochemistry

Integrated Omics Analyses Reveal Differential Gene Expression and Potential for Cooperation Between Denitrifying Polyphosphate and Glycogen Accumulating Organisms

Y. Wang, H. Gao, G. Wells

The paper investigates differential gene expression and ecological interactions between denitrifying polyphosphate and glycogen accumulating organisms in wastewater treatment processes, finding elevated nitrite reductase expression and potential cooperation in reducing nitric oxide.

bioRxiv · Jan 10, 2020Bioengineering

The kinase inhibitor AT9283 selectively kills colorectal cancer cells with hyperactive NRF2

L. Torrente, G. Maan, L. Casares, A. Jackson, T. Honda, G. Wells, E. Kulesskiy, J. Saarela, A. T. Dinkova-Kostova, L. de la Vega

The paper identifies AT9283 as a drug that selectively kills colorectal cancer cells with hyperactive NRF2, showing its potential as a therapeutic target.

bioRxiv · Oct 21, 2019 · PreprintCancer Biology

Integrated Low-Energy and Low Carbon Shortcut Nitrogen removal with Biological Phosphorus Removal for Sustainable Mainstream Wastewater Treatment

P. Roots, F. Sabba, A. Rosenthal, Y. Wang, Q. Yuan, L. Rieger, F. Yang, J. Kozak, H. Zhang, G. Wells

The paper demonstrates efficient combined nitrogen, phosphorus, and chemical oxygen demand removal in a wastewater treatment system using anaerobic-aerobic cycling and nitritation-denitritation without exogenous chemicals.

bioRxiv · Sep 19, 2019Bioengineering

Comammox Nitrospira are the dominant ammonia oxidizers in a mainstream low dissolved oxygen nitrification reactor

P. Roots, Y. Wang, A. Rosenthal, J. Griffin, F. Sabba, M. Petrovich, F. Yang, J. Kozak, H. Zhang, G. Wells

This study shows comammox Nitrospira dominate ammonia oxidation in a low dissolved oxygen nitrification reactor, outperforming conventional systems.

bioRxiv · Dec 21, 2018Bioengineering