Author

S. Caldera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:metagenomics· 3 Approach:deep learning· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. Langelier· 4 shared E. D. Crawford· 3 shared J. Quan· 3 shared R. Sit· 3 shared A. Lyden· 2 shared A. McGeever· 2 shared B. Dimitrov· 2 shared J. DeRisi· 2 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

C. Langelier

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Designing and implementing programmable depletion in sequencing libraries with DASHit

D. Dynerman, A. Lyden, J. Quan, S. Caldera, A. McGeever, B. Dimitrov, R. King, G. Cirola, M. Tan, R. Sit, M. van den Berge, H. A. M. Kerstjens, A. Faiz, S. Christenson, C. Langelier, , E. D. Crawford

The paper introduces DASHit, a software tool that designs CRISPR-based depletion targets to reduce high-abundance sequences in sequencing libraries, demonstrating its effectiveness across three species.

bioRxiv · Jan 12, 2020 · PreprintMicrobiology

Investigating Transfusion-Related Sepsis using Culture-Independent Metagenomic Sequencing

E. D. Crawford, J. Kamm, S. Miller, L. Li, S. Caldera, A. D. Lyden, D. Yokoe, A. Nichols, N. K. Tran, S. Barnhard, P. M. Conner, A. Nambiar, M. S. Zinter, M. Moayeri, P. Hayakawa Serpa, , C. Langelier

This study uses metagenomic sequencing to identify pathogens in transfusion-related sepsis cases, revealing a novel Acinetobacter species and demonstrating the utility of culture-independent methods.

bioRxiv · Sep 16, 2019Microbiology

FLASH: A next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences

J. Quan, C. Langelier, A. Kuchta, J. Batson, N. Teyssier, A. Lyden, S. Caldera, A. McGeever, B. Dimitrov, R. King, J. Wilheim, M. Murphy, L. Pesce Ares, K. A. Travisano, R. Sit, , E. D. Crawford

FLASH is a CRISPR-based diagnostic method that enhances detection of low-abundance antimicrobial resistance sequences in metagenomic data.

bioRxiv · May 12, 2019Microbiology

Microbiome and Antimicrobial Resistance Gene Dynamics in International Travelers

C. Langelier, M. Graves, K. L. Kalantar, S. Caldera, R. Durrant, M. Fisher, R. Backman, W. Tanner, J. DeRisi, D. Leung

This study uses metagenomic sequencing to track changes in gut microbiota and antimicrobial resistance genes in international travelers, finding increased resistance genes and Escherichia species without affecting microbial diversity.

bioRxiv · Dec 26, 2018Microbiology