Author

D. Leung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Bioengineering· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

A. Feng· 1 shared A. K. Grosskopf· 1 shared A. l. d'Aquino· 1 shared A. L. Hartman· 1 shared A. Radhakrishnan· 1 shared A. Rahat· 1 shared A. Shelton· 1 shared A. Singh· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Feng

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics

R. J. Carlson, J. J. Patten, G. Stefanakis, B. Y. Soong, A. Radhakrishnan, A. Singh, N. Thakur, G. K. Amarasinghe, N. Hacohen, C. F. Basler, D. Leung, C. Uhler, R. A. Davey, P. C. Blainey

This study uses single-cell image-based CRISPR screens to identify host factors regulating Ebola virus infection, revealing new therapeutic targets like UQCRB and STRAP.

bioRxiv · Apr 6, 2024 · PreprintMicrobiology

OsUVR8b, rather than OsUVR8a, plays a predominant role in rice UVR8-mediated UV-B response.

Y.-l. Chen, Y.-b. Zhong, D. Leung, X.-y. Yan, M.-n. Ouyang, Y.-z. Ye, S.-m. Li, X. Peng, E.-e. Liu

This study identifies OsUVR8b as the primary mediator of UV-B response in rice, showing it has a stronger role than OsUVR8a in growth inhibition and gene regulation under UV-B exposure.

bioRxiv · Dec 7, 2023Plant Biology

Injectable polymer-nanoparticle hydrogel for the sustained intravitreal delivery of bimatoprost

E. L. Meany, R. Andaya, S. Tang, C. M. Kasse, R. N. Fuji, A. K. Grosskopf, A. l. d'Aquino, J. T. Bartoe, R. Ybarra, A. Shelton, Z. Pederson, C. Hu, D. Leung, K. Nagapudi, S. Ubhayakar, , E. Appel

This paper develops an injectable polymer-nanoparticle hydrogel for sustained intravitreal delivery of bimatoprost, showing prolonged drug release and minimal inflammation in rabbits.

bioRxiv · Sep 8, 2022Bioengineering

Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1

M. Schwarz, D. A. Price, S. Ganaie, A. Feng, N. Mishra, R. Hoehl, F. Fatma, S. Stubbs, S. P. J. Whelan, X. Cui, T. Egawa, D. Leung, G. Amarasinghe, A. L. Hartman

This study identifies Lrp1 as a host factor required for Oropouche orthobunyavirus infection and suggests a broader role for Lrp1 in bunyavirus entry.

bioRxiv · Feb 26, 2022Microbiology

Situation of antibiotic resistance in Bangladesh and its association with resistance genes for horizontal transfer

K. S. Safain, G. S. Bhuyan, S. Tasnim, S. H. Hasib, R. Sultana, M. S. Islam, M. A. Mahmud-Un-Nabi, S. K. Sarker, F. A. Noor, A. Rahat, M. A. M. Bhuiyan, M. T. Islam, F. Manzoor, S. Anwar, D. Leung, , K. Mannoor

The study examines antibiotic resistance patterns and associated genes in clinical isolates from Bangladesh, finding high prevalence of MDR strains and specific resistance genes like CTXM-1 and ErmB.

bioRxiv · Apr 6, 2020 · PreprintMicrobiology

Microbiome and Antimicrobial Resistance Gene Dynamics in International Travelers

C. Langelier, M. Graves, K. L. Kalantar, S. Caldera, R. Durrant, M. Fisher, R. Backman, W. Tanner, J. DeRisi, D. Leung

This study uses metagenomic sequencing to track changes in gut microbiota and antimicrobial resistance genes in international travelers, finding increased resistance genes and Escherichia species without affecting microbial diversity.

bioRxiv · Dec 26, 2018Microbiology