S. Ghavami

Assessment of Stiffness-Dependent Autophagosome Formation and Apoptosis in Embryonal Rhabdomyosarcoma Tumor Cells

This study evaluates how matrix stiffness affects autophagosome formation and apoptosis in embryonal rhabdomyosarcoma cells using GelMA hydrogels.

Characterization Of Bitter Taste Receptor Dependent Autophagy in Oral Epithelial Cells

The paper characterizes T2R14-dependent autophagy in gingival epithelial cells using western blot and flow cytometry to assess autophagy flux.

Evaluation of Autophagy in conjunctival fibroblasts

The paper evaluates autophagy in conjunctival fibroblasts using immunocytochemistry, immunoblotting, and qPCR to understand its role in vernal keratoconjunctivitis.

Bitter taste receptor T2R14 and autophagy flux in gingival epithelial cells

This study shows that T2R14 downregulates autophagy flux in gingival epithelial cells and that S. mutans CSP-1 induces calcium release dependent on T2R14 and autophagy protein 7.

Assessment of autophagy in Leishmania parasites

This study develops methods to assess autophagy in Leishmania major parasites using transmission electron microscopy and flow cytometry with acridine orange dye.

A Lipidomics Approach to Determine the Role of Lipids and its Crosstalk with Autophagy in Lung Cancer Metastasis

The paper uses lipidomics to investigate the role of lipids and their interaction with autophagy in lung cancer metastasis.

The mitophagy receptor BNIP3L/Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.

This study shows Nix regulates muscle phenotype by coordinating mitophagy, ER-phagy, and nuclear calcium signaling, affecting insulin sensitivity and fiber-type composition.

A multi-omics analysis of glioma chemoresistance using a hybrid microphysiological model of glioblastoma

This study uses a hybrid microphysiological model to analyze glioma chemoresistance and identifies molecular changes associated with resistance mechanisms.

Differential Impact of Doxorubicin Dose on Cell Death and Autophagy Pathways during Acute Cardiotoxicity.

This study examines the effects of low- and high-dose doxorubicin on cardiac structure, function, and cell death pathways in mice, finding that high-dose DOX causes necrosis and autophagy inhibition, while low-dose activates caspase signaling.

Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation.

The paper shows that Nix-induced mitochondrial fission, mitophagy, and insulin resistance in myocytes are reversed by PKA phosphorylation.