Capturing G protein-coupled receptors into native lipid-bilayer nanodiscs using new diisobutylene/maleic acid (DIBMA) copolymers
C. Chu, C. Vargas, M. C. Barbosa, S. Sommerhage, G. F. Schroeder, S. Keller, M. Etzkorn
This paper introduces new DIBMA-based copolymers for extracting GPCRs into native lipid-bilayer nanodiscs, showing improved performance over existing polymers like SMA.
bioRxiv · Jan 20, 2024Biochemistry