Author

A. Bar-Even

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4 Microbiology· 2 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:E. coli· 4 Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Approach:comparative / phylogenetic analysis· 2 Approach:deep learning· 2 Assay:metabolomics· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2

Frequent Co-Authors

G. M. M. Stoffel· 2 shared H. He· 2 shared L. Calzadiaz Ramirez· 2 shared T. J. Erb· 2 shared A. Aspuru-Guzik· 1 shared A. Berger· 1 shared A. D. Hanson· 1 shared A. Fernie· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

G. M. M. Stoffel

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Engineering and Evolution of the Complete Reductive Glycine Pathway in Saccharomyces cerevisiae for Formate and CO2 Assimilation

V. R. Bysani, A. S. M. Alam, A. Bar-Even, F. Machens

This study engineers the complete reductive glycine pathway in yeast to enable formate and CO2 assimilation, achieving 8-fold improved growth through adaptive evolution and reverse-engineering.

bioRxiv · Jul 10, 2023 · PreprintBiochemistry

Design, construction and optimization of formaldehyde growth biosensors with broad application in Biotechnology

K. Schann, J. Bakker, M. Boinot, P. Kuschel, H. He, M. Nattermann, T. Erb, A. Bar-Even, S. Wenk

This paper designs and optimizes formaldehyde-detecting E. coli biosensors with broad applications in biotechnology and environmental monitoring.

bioRxiv · Jun 29, 2023Bioengineering

Emergence of NADP+-reducing enzymes in Escherichia coli central metabolism via adaptive evolution

M. Bouzon, V. Döring, I. Dubois, A. Berger, G. M. M. Stoffel, L. Calzadiaz Ramirez, S. Meyer, M. Foure, D. Roche, A. Perret, T. J. Erb, A. Bar-Even, S. N. Lindner

This study shows that adaptive evolution in E. coli can change cofactor specificity of enzymes, enabling NADPH regeneration without external sources, but is limited by thermodynamic constraints.

bioRxiv · Feb 8, 2021 · PreprintMicrobiology

Photorespiration pathways in a chemolithoautotroph

N. J. Claassens, G. Scarinci, A. Fischer, A. I. Flamholz, W. Newell, S. Frielingsdorf, O. Lenz, A. Bar-Even

This study identifies a novel photorespiration pathway in chemolithoautotrophic bacteria, revealing the glycerate pathway as the main route and the malate cycle as an oxidative alternative.

bioRxiv · May 8, 2020Microbiology

In vivo selection for formate dehydrogenases with high efficiency and specificity towards NADP+

L. Calzadiaz Ramirez, C. Calvo-Tusell, G. M. M. Stoffel, S. Lindner, S. Osuna, T. J. Erb, M. Garcia-Borras, A. Bar-Even, C. G. Acevedo-Rocha

This study uses in vivo selection to engineer formate dehydrogenases with high efficiency and specificity for NADP+ regeneration.

bioRxiv · Apr 2, 2020 · PreprintBiochemistry

Thioproline formation as a driver of formaldehyde toxicity in Escherichia coli

J. A. Patterson, H. He, J. S. Folz, Q. Lee, M. A. Wilson, O. Fiehn, S. D. Bruner, A. Bar-Even, A. D. Hanson

This study identifies thioproline formation as a key contributor to formaldehyde toxicity in E. coli and suggests PepP as a potential damage-control enzyme.

bioRxiv · Mar 19, 2020Biochemistry

Kingdom-wide comparison reveals conserved diurnal gene expression in Archaeplastida

C. Ferrari, S. Proost, M. Janowski, J. Becker, Z. Nikoloski, D. Bhattacharya, D. Price, T. Tohge, A. Bar-Even, A. Fernie, M. Stitt, M. Mutwil

The paper compares diurnal gene expression across nine Archaeplastida species, finding conserved transcriptional programs despite evolutionary divergence and lifestyle differences.

bioRxiv · Aug 15, 2018Evolutionary Biology

Quantum chemistry reveals the thermodynamic principles of redoxbiochemistry

A. Jinich, A. Flamholz, H. Ren, S.-J. Kim, B. Sanchez-Lengeling, C. A. R. Cotton, E. Noor, A. Aspuru-Guzik, A. Bar-Even

This study uses quantum chemistry to calculate redox potentials of biochemical reactions, revealing thermodynamic trends and explaining the role of NAD/NADP in cellular metabolism.

bioRxiv · Jan 9, 2018Biochemistry