S. M. Douglas

The paper shows that tightly clustering Fc gamma-receptors using DNA origami enhances phagocytosis by increasing receptor phosphorylation and downstream signaling efficiency.

The paper uses DNA origami to pattern synthetic T cell receptors and shows how spatial arrangement affects signaling sensitivity and kinetics.

The paper introduces molecular goniometers using DNA origami to precisely orient DNA-binding proteins for cryo-EM, achieving a 6.5 Å structure of BurrH.

This paper introduces amino and PEG-amino functionalized graphene oxide grids to improve sample concentration, distribution, and protection for cryo-EM.

The paper constructs a novel phagemid, pScaf, to produce custom DNA origami scaffolds with a smaller fixed region, enabling greater design flexibility.