Author

S. Markovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Feven· 1 shared A. Flohr· 1 shared A. Mayweg· 1 shared A. S. Mansfield· 1 shared A. Salomatov· 1 shared D. Epstein· 1 shared D. Owen· 1 shared D. Romashko· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Feven

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Resilient CD8+ T cells maintain a high cytotoxic capacity by balancing ROS via ME1 upregulation

J. K. Gicobi, Z. Mao, G. DeFranco, Y. Li, X. Liu, J. B. Hirdler, V. V. Vianzon, E. R. Dellacecca, M. A. Hsu, W. Barham, Y. H. Kim, A. Feven, W. S. Harmsen, Y. Yan, R. S. Dronca, , H. Dong

This paper identifies CX3CR1+ CD8+ T cells with low mitochondrial membrane potential as functionally resilient, showing high cytotoxicity and reduced ROS through ME1 upregulation, which enhances their anti-tumor activity.

bioRxiv · Nov 25, 2022 · PreprintImmunology

EGFR Oncogenes Expressed In Glioblastoma Are Activated As Covalent Dimers And Paradoxically Stimulated By Erlotinib

E. Buck, M. O'Connor, D. Romashko, A. Salomatov, N. Ishiyama, D. Epstein, A. Mayweg, A. Flohr, R. Iacone, T. Nicolaides, S. Markovic, J. Zhang

The paper identifies a mechanism by which extracellular domain EGFR mutations in glioblastoma are activated through covalent dimerization, rendering ATP-site inhibitors ineffective and paradoxically promoting proliferation.

bioRxiv · Oct 21, 2019 · PreprintCancer Biology