S. R. Ross

This study shows MLV can infect non-dividing primary dendritic cells, challenging the belief that gammaretroviruses require cell division for nuclear entry.

This study shows DNA damage and G2 phase arrest induce direct megakaryopoiesis from HSCs through a post-transcriptional mechanism, while impairing HSC maintenance.

The paper identifies IFI207 as a rapidly evolving antiviral factor that stabilizes STING, enhancing the host's response to viral infections.

This study shows that uracil DNA glycosylase 2 (UNG) repairs APOBEC3G-induced mutations in retroviral DNA in vivo, reducing G-to-A mutations and limiting viral integration.

This study shows APOBEC3A promotes tumorigenesis in mice and supports its role in causing mutations in human cancers.

This study shows that human APOBEC3G prevents the emergence of infectious endogenous retroviruses in mice, demonstrating its in vivo antiviral activity against ERVs.

This study identifies DDX41 as a sensor for retroviral RNA/DNA hybrids and shows its critical role in controlling MLV infection in vivo, alongside cGAS.